TULP2抗体—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08920(TULP2 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P08920(TULP2 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

The TULP2 (Tubby-like protein 2) antibody is a research tool designed to detect and study the TULP2 protein, a member of the Tubby-related protein family. TULP2. encoded by the *TULP2* gene in humans, shares structural homology with the Tubby protein, characterized by a conserved C-terminal β-barrel domain involved in membrane binding and lipid interactions. While the exact biological role of TULP2 remains under investigation, it is implicated in intracellular trafficking, signal transduction, and membrane-associated processes.

TULP2 is predominantly expressed in the testis, suggesting a potential role in spermatogenesis or male reproductive function. Studies link TULP2 to interactions with G proteins and phospholipids, hinting at its involvement in signaling pathways or vesicular transport. Dysregulation of TULP family proteins has been associated with metabolic disorders, obesity-related conditions, and sensory deficits, though specific disease connections for TULP2 are less defined.

Antibodies targeting TULP2 are utilized in techniques like Western blotting, immunohistochemistry, and immunofluorescence to assess protein expression, localization, and interaction partners. These tools help elucidate TULP2's physiological functions, particularly in reproductive biology and cellular trafficking mechanisms. Commercial TULP2 antibodies are typically validated for specificity using knockout controls or peptide blocking assays, ensuring reliability in experimental settings. Ongoing research aims to clarify its molecular mechanisms and potential clinical relevance.