TSC22D1抗体—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P08918(TSC22D1 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

The TSC22D1 antibody is a research tool designed to detect the TSC22 domain family member 1 (TSC22D1) protein, a member of the TSC22D family characterized by a conserved TSC22 domain. TSC22D1 is a transcriptional regulator implicated in diverse cellular processes, including proliferation, differentiation, apoptosis, and stress responses. It interacts with signaling pathways such as TGF-β, glucocorticoid receptor, and MAPK cascades, influencing gene expression. Studies highlight its role in organ development, fibrosis, immune regulation, and cancer, where it may act as both a tumor suppressor and promoter depending on context.

The antibody is widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to study TSC22D1 expression, localization, and interactions. Commercial antibodies are typically raised in rabbits or mice, targeting specific epitopes across human, mouse, or rat homologs. Research using these antibodies has revealed TSC22D1's involvement in diseases such as renal fibrosis, neurodegenerative disorders, and malignancies, underscoring its therapeutic potential. However, variability in antibody specificity requires careful validation to ensure accurate experimental outcomes. Overall, the TSC22D1 antibody is a critical reagent for exploring the protein's complex roles in health and disease.