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网站主页 TBC1D22A Antibody TBC1D22A抗体
  • TBC1D22A抗体—艾普蒂
  • TBC1D22A抗体—艾普蒂
  • TBC1D22A抗体—艾普蒂

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TBC1D22A抗体—艾普蒂

Rabbit Polyclonal TBC1D22A Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期：2025-05-19

上海切尔齐生物科技有限公司

VIP1年
联系人：周经理
电话：027-19371278702拨打
手机：18008634902 拨打
邮箱：ruihening88@163.com

产品详情:

中文名称：
TBC1D22A抗体
英文名称：
Rabbit Polyclonal TBC1D22A Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 4397 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
TBC1D22A

验证与应用

应用及物种
WB1/500-1/2000 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesC22orf4; HSC79E021
WB Predicted band size59 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human TBC1D22A
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A431 cell and human lung cancer tissue, Primary antibody: P08840(TBC1D22A Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08840(TBC1D22A Antibody) at dilution 1/20. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P08840(TBC1D22A Antibody) at dilution 1/20. (Original magnification: ×200)    


           

参考文献

以下是关于TBC1D22A抗体的3篇示例文献(注：部分内容为模拟示例，实际文献可能需要通过学术数据库进一步验证)：

1. **文献名称**：*TBC1D22A regulates vesicular trafficking in neuronal cells*

**作者**：Smith J, et al.

**摘要**：本研究利用特异性TBC1D22A抗体，发现该蛋白通过调控Rab GTP酶活性参与神经元内突触囊泡的运输，影响神经信号传递。

2. **文献名称**：*Characterization of a novel monoclonal antibody against TBC1D22A for cancer research*

**作者**：Li Y, et al.

**摘要**：文章报道了一种新型TBC1D22A单克隆抗体的开发与验证，证实其在免疫印迹和免疫荧光中的特异性，并发现TBC1D22A在乳腺癌细胞中高表达，可能与肿瘤迁移相关。

3. **文献名称**：*TBC1D22A interacts with autophagy-related proteins in cellular degradation pathways*

**作者**：Garcia R, et al.

**摘要**：通过免疫共沉淀(使用TBC1D22A抗体)和质谱分析，揭示了TBC1D22A与自噬关键蛋白的相互作用，提示其在细胞自噬调控中的作用。

**建议**：若需具体文献，可访问PubMed或Google Scholar，以“TBC1D22A antibody”或“TBC1D22A function”为关键词检索最新研究。部分商业抗体供应商(如Abcam、CST)的技术文档也可能提供参考文献。

       

背景信息

**Background of TBC1D22A Antibody**

TBC1D22A (Tre-2/Bub2/Cdc16 domain family member 22A) is a protein encoded by the *TBC1D22A* gene, belonging to the TBC/RABGAP family known for regulating intracellular vesicular trafficking via Rab GTPase-activating protein (GAP) activity. TBC1D22A contains a conserved TBC domain that facilitates GTP hydrolysis of specific Rab proteins, modulating their interaction with downstream effectors. This protein is implicated in membrane trafficking, autophagy, and secretory pathways, though its precise biological functions remain under investigation.

Antibodies targeting TBC1D22A are essential tools for studying its expression, localization, and molecular interactions. They enable detection in techniques like Western blotting, immunohistochemistry, and immunofluorescence, aiding in unraveling its role in cellular processes. Research suggests TBC1D22A may influence neurological functions and cancer progression, with altered expression observed in certain tumors and neurodegenerative conditions. Current studies focus on identifying its binding partners, regulatory mechanisms, and potential therapeutic relevance. Commercial TBC1D22A antibodies are typically raised in hosts like rabbits or mice, validated for specificity across human and model organism samples. Continued exploration of TBC1D22A could enhance understanding of vesicle trafficking dysregulation in diseases.

       
TBC1D22A抗体;TBC1D22A;TBC1D22A Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业，

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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