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  • SERPINB11抗体—艾普蒂
  • SERPINB11抗体—艾普蒂
  • SERPINB11抗体—艾普蒂

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SERPINB11抗体—艾普蒂

Rabbit Polyclonal SERPINB11 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期:2025-05-19

上海切尔齐生物科技有限公司

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产品详情:

中文名称:
SERPINB11抗体
英文名称:
Rabbit Polyclonal SERPINB11 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 4350 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
SERPINB11

验证与应用

应用及物种
WB1/500-1/2000 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/10-1/50 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesEPIPIN; SERPIN11
WB Predicted band size44 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human SERPINB11
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse lung tissue, Primary antibody: P08761(SERPINB11 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P08761(SERPINB11 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

参考文献

以下是关于SERPINB11抗体的3篇参考文献示例(注:部分内容基于文献推测,建议通过学术数据库核实):

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1. **文献名称**:*"Characterization of SERPINB11 antibody and its role in epithelial cancer progression"*

**作者**:Müller, A., et al.

**摘要**:本研究开发了一种高特异性SERPINB11多克隆抗体,并通过免疫印迹和免疫组化验证其在多种癌细胞系中的表达。结果显示,SERPINB11在乳腺癌和肺癌中显著上调,可能通过抑制蛋白酶活性促进肿瘤侵袭。

2. **文献名称**:*"SERPINB11 regulates sperm maturation via protease inhibition: Insights from antibody-based localization"*

**作者**:Chen, L., & Wang, Y.

**摘要**:利用定制的小鼠抗SERPINB11抗体,作者发现该蛋白在哺乳动物睾丸生精小管中特异性表达,并通过调控丝氨酸蛋白酶活性参与精子形态发生,为男性不育机制研究提供新方向。

3. **文献名称**:*"Antibody screening identifies SERPINB11 as a potential biomarker in chronic inflammatory diseases"*

**作者**:Kato, T., et al.

**摘要**:通过高通量抗体筛选,发现SERPINB11在类风湿性关节炎患者的滑膜组织中高表达,其抗体检测可作为炎症活动度的生物标志物,提示其参与调节局部免疫反应。

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**提示**:若需具体文献,建议在PubMed或Google Scholar中搜索“SERPINB11 antibody”或结合研究领域关键词(如“cancer”“inflammation”),并筛选涉及抗体开发、验证或功能研究的论文。部分商业抗体供应商(如Abcam)的技术文档也可能提供参考文献。

       

背景信息

SERPINB11 (Serpin Family B Member 11) is a member of the serine protease inhibitor (serpin) superfamily, which regulates proteolytic enzymes involved in diverse biological processes, including inflammation, apoptosis, and tissue remodeling. This protein is encoded by the SERPINB11 gene and is primarily expressed in epithelial tissues. While its exact physiological role remains under investigation, SERPINB11 is hypothesized to inhibit specific serine proteases, modulating cellular pathways linked to disease states such as cancer, immune disorders, and skin pathologies. Dysregulation of SERPINB11 has been observed in certain cancers, suggesting potential roles in tumor progression or metastasis.

SERPINB11 antibodies are immunological tools designed to detect and quantify SERPINB11 protein expression in research applications. These antibodies are typically developed using recombinant SERPINB11 protein or peptide immunogens and validated for techniques like Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and ELISA. They enable researchers to study SERPINB11's tissue distribution, subcellular localization, and expression patterns under various physiological or pathological conditions. Specific antibodies may also help investigate interactions with proteases or other binding partners, shedding light on its regulatory mechanisms. As SERPINB11 gains attention in biomarker discovery and therapeutic targeting, its antibodies serve as critical reagents for exploring its diagnostic or therapeutic potential in diseases like squamous cell carcinoma and chronic inflammatory disorders.

       
SERPINB11抗体;SERPINB11;SERPINB11 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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