LRRC57抗体—艾普蒂

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     Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: HT29 cells, Primary antibody: P08486(LRRC57 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P08486(LRRC57 Antibody) at dilution 1/40. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human brain  tissue using P08486(LRRC57 Antibody) at dilution 1/40. (Original magnification: ×200)    

  
  

LRRC57 (Leucine-Rich Repeat-Containing Protein 57) is a relatively understudied protein belonging to the leucine-rich repeat (LRR) superfamily, characterized by tandem repeats of 20–30 amino acids rich in leucine residues. These proteins are often involved in protein-protein interactions, cellular signaling, and structural organization. LRRC57 is predicted to contain an N-terminal LRR domain and a C-terminal coiled-coil region, suggesting roles in molecular scaffolding or complex assembly. However, its precise biological functions remain unclear, with limited literature linking it to specific pathways or diseases.

Antibodies targeting LRRC57 are primarily used as research tools to explore its expression, localization, and interactions. For example, studies have employed LRRC57 antibodies in techniques like Western blotting, immunofluorescence, and immunoprecipitation to detect endogenous LRRC57 in cell lines or tissues. Some reports suggest its potential involvement in transcriptional regulation or viral-host interactions, such as a proposed association with HPV E2 protein dynamics, though further validation is needed. Commercial LRRC57 antibodies are available from multiple suppliers (e.g., polyclonal antibodies from rabbit hosts), often validated for specificity using knockdown or knockout controls. However, researchers are advised to verify antibody performance in specific experimental contexts due to limited independent validation data. Ongoing research aims to clarify LRRC57's role in cellular processes and its relevance to human health.