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IFRD1抗体—艾普蒂

Rabbit Polyclonal IFRD1 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期:2025-05-19

上海切尔齐生物科技有限公司

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产品详情:

中文名称:
IFRD1抗体
英文名称:
Rabbit Polyclonal IFRD1 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 4130 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
IFRD1

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesPC4; TIS7
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human IFRD1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P08429(IFRD1 Antibody) at dilution 1/30. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human brain  tissue using P08429(IFRD1 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

参考文献

以下是关于IFRD1抗体的参考文献示例,包含文献名称、作者及摘要概述:

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1. **文献名称**: *"IFRD1 regulates skeletal muscle regeneration by modulating macrophage polarization"*

**作者**: Marinari, B., et al.

**摘要**: 研究通过Western blot和免疫组化分析IFRD1在肌肉损伤模型中的表达,利用特异性抗体证实IFRD1通过调控巨噬细胞极化促进组织修复,揭示其在炎症微环境中的关键作用。

2. **文献名称**: *"The role of IFRD1 in myogenic differentiation and muscle repair"*

**作者**: Tirone, F., et al.

**摘要**: 使用IFRD1抗体检测其在肌肉干细胞中的表达动态,发现IFRD1缺失导致肌细胞分化受阻,表明其通过调控转录因子活性参与再生过程,为肌肉疾病治疗提供靶点。

3. **文献名称**: *"IFRD1 as a prognostic biomarker in colorectal cancer: Immunohistochemical analysis"*

**作者**: Shang, Y., et al.

**摘要**: 通过抗IFRD1抗体进行免疫组化染色,发现结直肠癌组织中IFRD1高表达与患者不良预后显著相关,提示其可作为潜在肿瘤标志物。

4. **文献名称**: *"Characterization of a novel polyclonal antibody against IFRD1 for functional proteomics"*

**作者**: Smith, J., et al.

**摘要**: 报道一种新型兔源多克隆抗体的开发与验证,该抗体可特异性识别IFRD1蛋白,适用于免疫印迹、免疫沉淀及细胞定位研究,为后续功能研究提供工具。

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注:上述文献为示例,实际引用时需核实具体发表信息及内容准确性。

       

背景信息

The IFRD1 (Interferon-Related Developmental Regulator 1) antibody is a tool used to detect the IFRD1 protein, a member of the interferon-related developmental regulator family. IFRD1. also known as PC4 or TIS7. is encoded by the *IFRD1* gene and plays roles in cellular differentiation, tissue development, and immune response regulation. It is expressed in various tissues, including the nervous system, muscles, and immune cells, and is implicated in processes like neurogenesis, myogenesis, and inflammation. Studies suggest IFRD1 interacts with histone deacetylases (HDACs) and modulates transcriptional activity, influencing cell cycle progression and apoptosis.

The IFRD1 antibody is widely utilized in research to investigate its involvement in diseases. For instance, IFRD1 dysregulation has been linked to muscular dystrophies, neurodegenerative disorders, and cancer. In neuroscience, it is studied for its role in nerve regeneration and synaptic plasticity. The antibody enables detection via techniques such as Western blotting, immunohistochemistry, and immunofluorescence, aiding in protein localization and expression analysis. Validated antibodies are critical for ensuring specificity, often confirmed through knockout controls or siRNA knockdown experiments. Researchers rely on IFRD1 antibodies to explore its molecular mechanisms, therapeutic potential, and biomarker utility in pathological conditions, making it a key reagent in both basic and translational studies.

       
IFRD1抗体;IFRD1;IFRD1 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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