Urantide/669089-53-6/选择性竞争尿素II受体拮抗剂Urantide

Product Name：Urantide

CAS No.：669089-53-6

Synonyms.：选择性竞争尿素II受体拮抗剂Urantide

Catalog No.：PYC-244

Description：Urantide是一种具有选择性和竞争性的拮抗剂多肽，其由8个氨基酸组成，序列中含有一对二硫键。Urantide可阻断大鼠体外胸主动脉中人尿紧张素-II (hU-II) 诱导的收缩。Urantide 可以用于研究 hU-II 在哺乳动物心血管系统中 (病理) 生理作用。同时Urantide在钙元素测定中充当部分激动剂的作用。

Urantide is a selective and competitive antagonist peptide consisting of 8 amino acids with a pair of disulfide bonds in its sequence. Urantide can block the contraction induced by human urinary angiotensin II (hU-II) in the thoracic aorta of rats in vitro. Urantide can be used to study the (pathological) physiological effects of hU-II in the mammalian cardiovascular system. At the same time, Urantide acts as a partial agonist in calcium element determination.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	D-Pen-F-{D-Trp}-Orn-YCV(Disulfide bridge: 2-7)
Sequence(3-letter code)	H-Asp-Pen-Phe-{D-Trp}-Orn-Tyr-Cys-Val-OH(Disulfide bridge: 2-7)
Peptide Structure
Molecular Formula	C51H68N10O12S2
Molecular Weight	1077.28

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