TRMT112抗体—艾普蒂 新品

The TRMT112 antibody is a valuable tool for studying the TRMT112 protein, a highly conserved methyltransferase adaptor involved in RNA modification and cellular processes. TRMT112 (tRNA methyltransferase 112) acts as a binding partner for multiple enzymes, including tRNA methyltransferases (e.g., TRMT11. TRMT112-TRMT11 complex) and the 18S rRNA methyltransferase WBSCR22. facilitating their stability and catalytic activity. It plays a critical role in post-transcriptional RNA modifications, such as N2-methylguanosine (m2G) and N7-methylguanosine (m7G), which are essential for ribosome biogenesis, tRNA maturation, and translational fidelity. Dysregulation of TRMT112 has been linked to neurodevelopmental disorders (e.g., Williams-Beuren syndrome) and cancer progression. The TRMT112 antibody enables detection and quantification of TRMT112 expression in various experimental models (e.g., Western blot, immunofluorescence), aiding research on its molecular interactions, tissue distribution, and pathological mechanisms. Its specificity for human, mouse, and rat homologs makes it widely applicable in studies of RNA epigenetics, gene regulation, and disease biomarkers.