基本信息 产品详情 公司简介 推荐产品
  • 首页
  • 个人中心
  • 委托采购
  • 采购清单
网站主页 GOLGA5抗体 GOLGA5抗体
  • GOLGA5抗体—艾普蒂
  • GOLGA5抗体—艾普蒂
  • GOLGA5抗体—艾普蒂

1/3

GOLGA5抗体—艾普蒂

Rabbit Polyclonal GOLGA5 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期：2025-05-18

上海切尔齐生物科技有限公司

非会员
联系人：周***
电话：027***
手机：180***
邮箱：rui***

产品详情:

中文名称：
GOLGA5抗体
英文名称：
Rabbit Polyclonal GOLGA5 Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 3175 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
GOLGA5

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/20-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesRFG5; GOLIM5; ret-II
WB Predicted band size83 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human GOLGA5
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: A549 cell lysate, Primary antibody: P06580(GOLGA5 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 90 seconds    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P06580(GOLGA5 Antibody) at dilution 1/20. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P06580(GOLGA5 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

参考文献

以下是3篇涉及GOLGA5抗体的文献示例(部分信息为模拟简化版，实际引用需核实原文)：

---

1. **文献名称**: *GOLGA5 as a novel biomarker in prostate cancer: Golgi structure and antibody validation*

**作者**: Smith J, et al.

**摘要**: 本研究通过开发兔源多克隆GOLGA5抗体，验证其在前列腺癌细胞中定位高尔基体的特异性。Western blot检测到约75 kDa的条带，免疫荧光显示癌细胞中高尔基体碎片化，提示GOLGA5表达异常与癌症进展相关。

2. **文献名称**: *Characterization of GOLGA5 autoantibodies in autoimmune disorders*

**作者**: Lee S, et al.

**摘要**: 利用重组人GOLGA5蛋白筛选系统性红斑狼疮患者血清，发现部分患者存在抗GOLGA5自身抗体。研究提示此类抗体可能干扰高尔基体功能，为自身免疫病理机制提供新线索。

3. **文献名称**: *Role of GOLGA5 in neuronal development: Insights from antibody-mediated knockdown*

**作者**: Chen R, et al.

**摘要**: 采用单克隆GOLGA5抗体阻断蛋白功能，发现其抑制神经元突触形成，证明GOLGA5通过调控囊泡运输参与神经发育，抗体工具为研究高尔基体动态提供关键手段。

---

**注意**：以上为示例模板，实际文献需通过PubMed/Google Scholar检索关键词“GOLGA5 antibody”或“GOLGA5 immunolocalization”获取，并核对作者、期刊及具体实验细节。

       

背景信息

The Golgin A5 (GOLGA5) antibody is a tool used to detect GOLGA5. a member of the golgin family of proteins localized to the Golgi apparatus. GOLGA5. also known as RET ligand 4 (RETL4), is characterized by its coiled-coil domains and plays a role in maintaining Golgi structure, vesicle trafficking, and protein sorting. It interacts with other golgins and Rab GTPases to mediate tethering and fusion events critical for Golgi organization.

GOLGA5 antibodies are widely utilized in research to study Golgi dynamics, cellular stress responses, and cancer biology. Notably, GOLGA5 gained attention due to its involvement in chromosomal rearrangements, particularly the RET-GOLGA5 fusion in thyroid and other cancers, which drives oncogenic signaling. Antibodies targeting GOLGA5 help identify such fusion proteins and assess Golgi integrity in disease models.

In autoimmune contexts, anti-GOLGA5 autoantibodies have been reported in subsets of patients with Sjögren’s syndrome or systemic lupus erythematosus, though their clinical significance remains under investigation. Commercial GOLGA5 antibodies are validated for techniques like Western blotting, immunofluorescence, and immunohistochemistry, often serving as Golgi markers. Researchers must consider potential cross-reactivity with homologous golgins and validate specificity using knockout controls. Ongoing studies explore its roles in neurodegeneration, viral infection, and Golgi-targeted therapies.

       
GOLGA5抗体;GOLGA5;GOLGA5 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业，

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

GOLGA5抗体相关厂家报价

内容声明
official 进入官方账号
拨打电话 立即询价