SLC2A8抗体—艾普蒂新品

Rabbit Polyclonal SLC2A8 Antibody

询价 20μl 起订

50μl 起订

100μl 起订

上海更新日期：2025-05-18

上海切尔齐生物科技有限公司

VIP1年

联系人：周经理

电话：027-19371278702拨打

手机：18008634902 拨打

邮箱：ruihening88@163.com

产品详情:

中文名称：: SLC2A8抗体

英文名称：: Rabbit Polyclonal SLC2A8 Antibody

品牌：: 艾普蒂

产地：: 武汉

保存条件：: Stored at -20°C for 3169 year. Avoid repeated freeze / thaw cycles.

产品类别：: 抗体

重组：: 否

应用：: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA

种属反应性：: Human,Mouse,Rat

宿主：: Rabbit

偶联物：: 无

靶点：: SLC2A8

验证与应用

应用及物种

WB	咨询技术	Human,Mouse,Rat
IF	咨询技术	Human,Mouse,Rat
IHC	1/30-1/150	Human,Mouse,Rat
ICC	技术咨询	Human,Mouse,Rat
FCM	咨询技术	Human,Mouse,Rat
Elisa	1/5000-1/10000	Human,Mouse,Rat

产品详情

Aliases	GLUT8; GLUTX1
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human SLC2A8
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P06572(SLC2A8 Antibody) at dilution 1/20. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P06572(SLC2A8 Antibody) at dilution 1/20. (Original magnification: ×200)

参考文献

以下是关于SLC2A8抗体的3篇参考文献(内容基于公开研究整理，非真实文献)：

1. **文献名称**：*Role of SLC2A8 in Testicular Glucose Transport and Spermatogenesis*

**作者**：Li, X. et al.

**摘要**：通过免疫组化和Western blot分析，研究SLC2A8抗体在小鼠睾丸组织中的特异性表达，发现其定位于精子细胞，提示其在睾丸葡萄糖代谢和精子形成中的作用。

2. **文献名称**：*SLC2A8 Overexpression in Breast Cancer: A Prognostic Marker*

**作者**：Chen, Y. & Wang, H.

**摘要**：利用SLC2A8抗体对乳腺癌组织进行免疫染色，发现SLC2A8蛋白高表达与肿瘤转移和患者预后不良显著相关，提示其作为潜在治疗靶点。

3. **文献名称**：*SLC2A8 Antibody Validation in Neuronal Glucose Uptake Studies*

**作者**：Smith, J. et al.

**摘要**：验证SLC2A8抗体在大脑神经元中的特异性，证实其参与神经元葡萄糖转运，并发现其在阿尔茨海默病模型中的表达异常。

如需具体文献，建议通过PubMed或Google Scholar以“SLC2A8 antibody”或“GLUT8 antibody”为关键词检索。

背景信息

The SLC2A8 antibody targets the solute carrier family 2 member 8 (SLC2A8), also known as glucose transporter 8 (GLUT8), encoded by the SLC2A8 gene. GLUT8 is a member of the facilitative glucose transporter (GLUT) family, which mediates cellular glucose uptake. Structurally, it contains 12 transmembrane domains characteristic of GLUT proteins. Unlike other GLUT isoforms, GLUT8 is primarily localized intracellularly, residing in endoplasmic reticulum, Golgi, or lysosomal membranes, and may require trafficking to the cell surface under specific conditions. It is highly expressed in testis, brain, liver, and adipose tissue, suggesting roles in energy metabolism and neuroendocrine function.

SLC2A8 antibodies are essential tools for studying GLUT8's physiological and pathological roles. Research indicates its involvement in insulin-regulated glucose transport, particularly in neurons and reproductive tissues. Dysregulation of GLUT8 has been linked to metabolic disorders, such as diabetes and obesity, as well as neurodegenerative diseases like Alzheimer's. In reproductive biology, GLUT8 is implicated in sperm maturation and ovarian follicle development.

Antibodies against SLC2A8 enable detection via Western blotting, immunohistochemistry, and immunofluorescence, aiding investigations into its expression patterns and subcellular localization. These studies help elucidate GLUT8's contribution to cellular glucose homeostasis and its potential as a therapeutic target. However, functional redundancy with other GLUT isoforms and context-dependent regulatory mechanisms necessitate careful validation of antibody specificity in experimental models.

SLC2A8抗体;SLC2A8;SLC2A8 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业，

成立日期	(1年)
注册资本	20万人民币
员工人数	1-10人
年营业额	￥ 100万以内
经营模式	贸易,工厂,试剂,定制,服务
主营行业	抗体,蛋白组学,细胞生物学