GLCCI1抗体—艾普蒂

+ +

•  

   

     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human cerebella tissue lysate, Primary antibody: P06567(GLCCI1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    

  
  

The GLCCI1 (Glucocorticoid-Induced Transcript 1 Protein) antibody is a research tool used to detect and study the GLCCI1 protein, which plays a role in glucocorticoid signaling pathways. GLCCI1 was initially identified as a gene induced by glucocorticoids, steroid hormones critical for regulating inflammation, metabolism, and immune responses. The protein is implicated in mediating glucocorticoid effects, particularly in immune cells, and may influence sensitivity to glucocorticoid therapy, a cornerstone treatment for inflammatory and autoimmune disorders like asthma and rheumatoid arthritis.

Structurally, GLCCI1 contains conserved domains suggesting involvement in protein-protein interactions, though its precise molecular mechanisms remain under investigation. Research has linked GLCCI1 polymorphisms to altered glucocorticoid responses in certain populations, highlighting its potential as a biomarker for predicting therapeutic outcomes. Antibodies targeting GLCCI1 enable its detection in techniques such as Western blotting, immunohistochemistry, and flow cytometry, aiding studies on its expression patterns in tissues or disease models. Current studies focus on understanding how GLCCI1 modulates glucocorticoid receptor activity, cellular stress responses, and its role in diseases with glucocorticoid resistance. These insights could inform personalized treatment strategies, optimizing glucocorticoid efficacy while minimizing side effects.