FAM98A抗体—艾普蒂

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human breast cancer tissue, Human liver cancer tissue and Human lung adenocarcinoma tissue lysates, Primary antibody: P06501(FAM98A Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P06501(FAM98A Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

FAM98A (family with sequence similarity 98 member A) is a relatively understudied protein encoded by the FAM98A gene, which is conserved across vertebrates and implicated in various cellular processes. The FAM98A antibody is a crucial tool for investigating the protein's expression, localization, and functional roles. Studies suggest FAM98A participates in regulating cell cycle progression, intracellular signaling, and cell migration. It has been linked to interactions with microtubule-associated proteins and RNA-binding proteins, hinting at roles in cytoskeletal organization or RNA metabolism.

Research using FAM98A antibodies has revealed its widespread tissue distribution, with elevated expression in organs like the brain, liver, and kidneys. In disease contexts, FAM98A has been associated with cancers, including colorectal and hepatocellular carcinomas, where its dysregulation may influence tumor progression. Antibody-based techniques (e.g., Western blot, immunofluorescence, immunoprecipitation) have been instrumental in mapping its subcellular localization, primarily to the cytoplasm and occasionally nuclear compartments.

Recent studies also explore FAM98A's potential involvement in neurological disorders and viral infections, though mechanistic details remain limited. Commercial FAM98A antibodies are typically validated for specificity using knockout cell lines or siRNA knockdowns. Challenges persist in fully elucidating its molecular interactions and pathways, underscoring the antibody's ongoing importance in driving fundamental and translational research.