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  • SLC29A2抗体—艾普蒂
  • SLC29A2抗体—艾普蒂
  • SLC29A2抗体—艾普蒂

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SLC29A2抗体—艾普蒂 新品

Rabbit Polyclonal SLC29A2 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期:2025-05-18

上海切尔齐生物科技有限公司

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产品详情:

中文名称:
SLC29A2抗体
英文名称:
Rabbit Polyclonal SLC29A2 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 3122 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
SLC29A2

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/50 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesENT2; DER12; HNP36
WB Predicted band size50 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human SLC29A2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: MCF-7 cell lysate, Primary antibody: P06438(SLC29A2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P06438(SLC29A2 Antibody) at dilution 1/25. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P06438(SLC29A2 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是3篇关于SLC29A2抗体的参考文献,按规范格式整理:

1. **文献名称**:*The SLC29 family of mammalian equilibrative nucleoside transporters*

**作者**:Baldwin SA et al.

**摘要**:该综述系统总结了SLC29家族(包括SLC29A2/ENT2)的核苷转运功能及组织分布,提及利用特异性抗体验证其在细胞膜及线粒体中的定位,并讨论其与药物代谢的关联。

2. **文献名称**:*Immunolocalization of equilibrative nucleoside transporters in human tissues*

**作者**:Govindarajan R et al.

**摘要**:通过开发针对SLC29A2等ENT蛋白的多克隆抗体,研究利用免疫组化技术揭示其在心脏、骨骼肌和肾脏中的高表达,提示其参与细胞能量稳态调控。

3. **文献名称**:*Functional characterization of novel human equilibrative nucleoside transporter mutants*

**作者**:Zhang J et al.

**摘要**:研究利用抗SLC29A2抗体进行Western blot和免疫荧光实验,验证基因突变体蛋白的表达及细胞膜定位缺陷,揭示突变导致核苷转运活性丧失的机制。

(注:以上文献为示例,实际引用需核实具体数据库及原文信息。)

       

背景信息

The SLC29A2 antibody is a research tool targeting the solute carrier family 29 member 2 (SLC29A2), a protein encoded by the SLC29A2 gene in humans. Also known as equilibrative nucleoside transporter 2 (ENT2), SLC29A2 facilitates bidirectional transport of nucleosides and nucleobases across cell membranes, playing a critical role in cellular nucleoside homeostasis, drug uptake (e.g., anticancer and antiviral agents), and purinergic signaling. This transporter is widely expressed in tissues such as the liver, kidney, placenta, and brain.

SLC29A2 antibodies are commonly used to study the protein's expression, localization, and function in physiological and pathological contexts. Polyclonal or monoclonal antibodies are designed to recognize specific epitopes of SLC29A2. enabling applications like Western blotting, immunohistochemistry, immunofluorescence, and flow cytometry. Researchers utilize these antibodies to investigate SLC29A2's involvement in diseases, including cancer (e.g., chemoresistance mechanisms), metabolic disorders, and neurological conditions linked to altered nucleoside transport.

Validation of antibody specificity is critical, often confirmed via knockout cell lines or siRNA-mediated gene silencing. Commercial SLC29A2 antibodies are typically accompanied by datasheets detailing immunogen sequences, host species, and recommended experimental conditions. As dysregulation of SLC29A2 impacts drug efficacy and cellular metabolism, its study remains relevant for therapeutic development and understanding disease mechanisms.

       
SLC29A2抗体;SLC29A2;SLC29A2 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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