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  • SLC22A24抗体—艾普蒂
  • SLC22A24抗体—艾普蒂
  • SLC22A24抗体—艾普蒂

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SLC22A24抗体—艾普蒂

Rabbit Polyclonal SLC22A24 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期:2025-05-16

上海切尔齐生物科技有限公司

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产品详情:

中文名称:
SLC22A24抗体
英文名称:
Rabbit Polyclonal SLC22A24 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 2288 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
SLC22A24

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesNET46
WB Predicted band size62 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human SLC22A24
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: 293T cell, Mouse liver tissue, Raji cell lysates, Primary antibody: P02664(SLC22A24 Antibody) at dilution 1/1350, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P02664(SLC22A24 Antibody) at dilution 1/80. (Original magnification: ×200)    


           

参考文献

以下是关于SLC22A24抗体的3篇假设性参考文献示例(注:SLC22A24相关研究较少,实际文献可能需要通过数据库检索验证):

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1. **文献名称**:*"Characterization of a Novel Polyclonal Antibody for SLC22A24 in Human Renal Tissue"*

**作者**:Smith J, et al.

**摘要**:本研究开发并验证了一种针对SLC22A24蛋白的多克隆抗体,通过免疫组化及Western blot证实其在人肾脏组织中的特异性表达,提示SLC22A24可能在肾脏有机溶质转运中发挥作用。

2. **文献名称**:*"SLC22A24 as a Uremic Toxin Transporter: Insights from Antibody-Based Knockdown Models"*

**作者**:Chen L, et al.

**摘要**:利用抗SLC22A24的siRNA和抗体阻断实验,揭示了该蛋白在肝细胞中对尿毒症毒素(如硫酸对甲酚)的外排功能,为慢性肾病代谢研究提供新靶点。

3. **文献名称**:*"Tissue Distribution and Evolutionary Conservation of SLC22A24: A Comparative Study Using Immunohistochemistry"*

**作者**:Garcia R, et al.

**摘要**:通过跨物种抗体交叉反应实验,发现SLC22A24在哺乳动物肝脏和肠道中高度保守,可能参与胆汁酸或药物代谢产物的跨膜转运。

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**提示**:若需真实文献,建议在PubMed或Google Scholar中检索关键词“SLC22A24 antibody”或“SLC22A24 function”,并筛选涉及抗体开发/应用的实验研究。部分相关研究可能整合在SLC22家族综述中。

       

背景信息

The SLC22A24 antibody is a research tool designed to detect and study the solute carrier family 22 member 24 (SLC22A24) protein, a relatively undercharacterized transporter within the SLC22 family. This family encompasses membrane proteins involved in the transport of endogenous compounds, xenobiotics, and drugs across cellular membranes, primarily in excretory organs like the kidney and liver. SLC22A24. though less studied compared to other members (e.g., SLC22A1/OCT1 or SLC22A6/OAT1), is hypothesized to play roles in organic anion/cation transport, potentially influencing drug disposition, detoxification, or metabolic pathways. Its expression patterns, substrate specificity, and physiological relevance remain areas of active investigation.

The SLC22A24 antibody is typically developed for applications such as Western blotting, immunohistochemistry, or immunofluorescence to localize the protein in tissues or assess its expression levels under varying conditions. Its utility lies in elucidating SLC22A24's tissue distribution, regulatory mechanisms, and involvement in disease contexts, such as renal dysfunction, metabolic disorders, or drug resistance. Validation of antibody specificity (e.g., via knockout controls) is critical due to potential cross-reactivity within the SLC22 family. Research using this antibody aims to clarify SLC22A24's biological and pharmacological significance, bridging gaps in understanding solute carrier biology and therapeutic targeting.

       
SLC22A24抗体;SLC22A24;SLC22A24 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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