TMEM248抗体—艾普蒂

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A172 and HEPG2 cell lysates, Primary antibody: P02660(TMEM248 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P02660(TMEM248 Antibody) at dilution 1/25. (Original magnification: ×200)    

  
  

The TMEM248 antibody is designed to target the transmembrane protein 248 (TMEM248), a poorly characterized protein encoded by the *TMEM248* gene in humans. TMEM248 is a member of the transmembrane (TMEM) protein family, which comprises diverse proteins involved in cellular processes such as membrane transport, signaling, and organelle organization. Structurally, TMEM248 is predicted to contain multiple transmembrane domains, suggesting its potential role in membrane-associated functions. However, its precise physiological role remains unclear. Limited studies associate TMEM248 with cellular stress responses, immune regulation, and possibly cancer progression, though mechanistic insights are sparse.

The TMEM248 antibody is primarily used in research to detect and visualize the protein's expression, localization, and interactions in cells or tissues. It has applications in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Commercial TMEM248 antibodies are typically produced in hosts such as rabbits or mice, with validation data confirming specificity through knockdown/knockout controls or peptide blocking assays. Researchers utilize these antibodies to explore TMEM248's expression patterns in disease models, particularly in cancers or immune-related conditions, aiming to clarify its biological relevance. Despite its limited characterization, TMEM248 remains a subject of interest for unraveling novel membrane protein functions, and its antibody serves as a critical tool for advancing these investigations.