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  • CHST10抗体—艾普蒂
  • CHST10抗体—艾普蒂
  • CHST10抗体—艾普蒂

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CHST10抗体—艾普蒂

Rabbit Polyclonal CHST10 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期：2025-05-16

上海切尔齐生物科技有限公司

VIP1年
联系人：周经理
电话：027-19371278702拨打
手机：18008634902 拨打
邮箱：ruihening88@163.com

产品详情:

中文名称：
CHST10抗体
英文名称：
Rabbit Polyclonal CHST10 Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 2254 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
CHST10

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/100-1/300 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesHNK1ST; HNK-1ST
WB Predicted band size42 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human CHST10
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: PC-3 cell lysate, Primary antibody: P02518(CHST10 Antibody) at dilution 1/900, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P02518(CHST10 Antibody) at dilution 1/120. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P02518(CHST10 Antibody) at dilution 1/120. (Original magnification: ×200)    


           

参考文献

以下是关于CHST10抗体的虚构参考文献示例(仅供示例参考，非真实文献)：

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1. **文献名称**：*CHST10 Expression in Hepatocellular Carcinoma Correlates with Tumor Metastasis*

**作者**：Liu X, Wang R, Chen L.

**摘要**：通过CHST10抗体的免疫组化分析，研究发现CHST10在肝癌组织中显著高表达，并与肿瘤转移和患者不良预后相关。体外实验显示，抑制CHST10可降低癌细胞的侵袭能力。

2. **文献名称**：*Role of CHST10 in Chondroitin Sulfate Biosynthesis and Neuronal Development*

**作者**：Tanaka K, et al.

**摘要**：利用CHST10抗体的Western blot和免疫荧光技术，证实CHST10在小鼠脑组织中特异性表达，调控硫酸软骨素的磺酸化修饰，影响神经元突触的形成与功能。

3. **文献名称**：*CHST10 as a Biomarker for Inflammatory Bowel Disease Progression*

**作者**：Garcia M, et al.

**摘要**：通过CHST10抗体对结肠活检样本的染色分析，发现CHST10在炎症性肠病患者的肠上皮细胞中异常上调，其表达水平与疾病严重程度呈正相关。

4. **文献名称**：*Antibody-Based Inhibition of CHST10 Suppresses Breast Cancer Cell Migration*

**作者**：Patel S, Lee H.

**摘要**：研究使用CHST10抗体阻断其功能，发现可显著抑制乳腺癌细胞迁移，表明CHST10通过调节细胞外基质的磺酸化促进肿瘤侵袭。

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(注：以上内容为模拟示例，实际文献需通过学术数据库查询。)

       

背景信息

The CHST10 antibody is a research tool targeting carbohydrate sulfotransferase 10 (CHST10), an enzyme involved in glycosaminoglycan (GAG) modification. CHST10. also known as chondroitin sulfotransferase 5. catalyzes the transfer of sulfate groups to chondroitin, a critical component of extracellular matrices and cell surfaces. This sulfation modulates cellular interactions, signaling, and tissue organization, particularly in neural and musculoskeletal systems. CHST10 is implicated in neurodevelopment, inflammation, and cancer metastasis due to its role in regulating sulfated GAG structures.

CHST10 antibodies are primarily used in biomedical research to detect CHST10 protein expression, localization, and post-translational modifications. They enable studies on CHST10's function in physiological and pathological contexts, including neurodegenerative diseases (e.g., Alzheimer’s), tumor microenvironments, and cartilage homeostasis. Commercial CHST10 antibodies are typically developed in hosts like rabbits or mice, validated via Western blot, immunohistochemistry, or immunofluorescence. However, specificity challenges may arise due to homology within the sulfotransferase family. Recent studies highlight its potential as a biomarker or therapeutic target, driving demand for reliable antibodies. Researchers prioritize validation using knockout controls to confirm target specificity in experimental models.

       
CHST10抗体;CHST10;CHST10 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业，

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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