GATD3B抗体—艾普蒂

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     Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-5: HEPG2, K562, Hela, A549 and 293T cell lysates, Primary antibody: P02432(GATD3B Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P02432(GATD3B Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

The GATD3B antibody is a research tool designed to detect and study the GATD3B (Glycogen Acetyltransferase Domain-Containing Protein 3B), a protein implicated in cellular processes such as post-translational modification and metabolic regulation. GATD3B belongs to the GATD protein family, characterized by conserved acetyltransferase-like domains, though its precise enzymatic activity remains under investigation. It is hypothesized to play a role in glycogen metabolism or protein acetylation, potentially influencing energy homeostasis, cellular stress responses, or epigenetic regulation.

The antibody is typically produced in hosts like rabbits or mice using immunogenic peptides or recombinant protein fragments specific to GATD3B. It is validated for applications such as Western blotting, immunofluorescence, or immunohistochemistry to determine protein expression, localization, and tissue distribution. Studies employing this antibody often focus on metabolic disorders, cancer, or neurodegenerative diseases, where dysregulation of acetylation pathways or glycogen dynamics may contribute to pathogenesis.

Researchers rely on GATD3B antibodies to explore its interaction networks, knockout/knockdown phenotypes, and potential therapeutic relevance. Specificity is confirmed using controls like GATD3B-deficient cell lines or tissues. As research progresses, this antibody aids in unraveling GATD3B's functional significance, bridging gaps in understanding its role in health and disease.