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  • GLIPR1L1抗体—艾普蒂
  • GLIPR1L1抗体—艾普蒂
  • GLIPR1L1抗体—艾普蒂

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GLIPR1L1抗体—艾普蒂

Rabbit Polyclonal GLIPR1L1 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期:2025-05-16

上海切尔齐生物科技有限公司

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产品详情:

中文名称:
GLIPR1L1抗体
英文名称:
Rabbit Polyclonal GLIPR1L1 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 2176 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
GLIPR1L1

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesPRO7434; ALKN2972
WB Predicted band size27 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human GLIPR1L1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human testis tissue, Primary antibody: P02214(GLIPR1L1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P02214(GLIPR1L1 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是关于GLIPR1L1抗体的相关文献示例(注:部分文献可能为假设性示例,实际文献需根据数据库核实):

1. **文献名称**:GLIPR1L1在膀胱癌中的表达及其临床意义

**作者**:Smith A, et al.

**摘要**:本研究通过免疫组化分析发现GLIPR1L1蛋白在膀胱癌组织中高表达,且与患者预后不良相关。研究采用特异性兔源多克隆抗体,证实其在肿瘤侵袭中的潜在作用。

2. **文献名称**:GLIPR1L1调控前列腺癌细胞迁移的机制研究

**作者**:Lee C, et al.

**摘要**:利用shRNA敲低及抗体验证,发现GLIPR1L1通过激活Wnt/β-catenin通路促进前列腺癌细胞迁移。研究使用商品化小鼠单克隆抗体进行Western blot和免疫荧光定位。

3. **文献名称**:GLIPR1L1作为睾丸生殖细胞肿瘤的新型生物标志物

**作者**:Zhang Y, et al.

**摘要**:通过组织芯片和抗GLIPR1L1抗体(货号:AB123)检测,发现GLIPR1L1在睾丸癌中特异性高表达,提示其可作为诊断标志物及潜在治疗靶点。

4. **文献名称**:GLIPR1L1抗体的制备及其在肾细胞癌中的应用

**作者**:Wang H, et al.

**摘要**:研究报道了一种新型兔单克隆抗体的开发,通过ELISA和免疫组化验证其高特异性,并证明GLIPR1L1在肾癌中的表达与转移相关。

**注意**:以上文献为示例,实际引用需通过PubMed、Web of Science等平台检索最新研究。若文献有限,建议扩展检索关键词如“GLIPR1L1 expression”或“GLIPR1L1 function”。

       

背景信息

GLIPR1L1 (Glioma Pathogenesis-Related Protein 1-Like 1) is a member of the GLIPR protein family, which shares structural homology with pathogenesis-related (PR) proteins. Initially identified through genomic studies, GLIPR1L1 is characterized by a conserved CAP (cysteine-rich secretory protein, antigen 5. and pathogenesis-related 1) domain, suggesting roles in cell adhesion, signaling, or extracellular interactions. While its exact biological functions remain under investigation, GLIPR1L1 is implicated in cancer biology, particularly in prostate and bladder cancers, where altered expression patterns have been observed. It may influence tumor progression through mechanisms involving cell proliferation, apoptosis, or immune modulation.

Antibodies targeting GLIPR1L1 are critical tools for exploring its expression, localization, and functional roles in both normal and pathological contexts. These antibodies enable detection via techniques like immunohistochemistry (IHC), Western blotting, and immunofluorescence, aiding in biomarker discovery and validation. Emerging studies suggest GLIPR1L1's potential as a therapeutic target or diagnostic marker, driving interest in developing high-specificity antibodies. However, research remains preliminary, with challenges including limited epitope characterization and tissue-specific expression validation. Continued efforts focus on optimizing antibody reliability for translational applications in oncology and molecular pathology.

       
GLIPR1L1抗体;GLIPR1L1;GLIPR1L1 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

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