TESC抗体—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P02184(TESC Antibody) at dilution 1/25. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P02184(TESC Antibody) at dilution 1/25. (Original magnification: ×200)    

  
  

TESC antibody targets the protein Tescalcin, encoded by the *TESC* gene, which plays a regulatory role in cellular processes such as differentiation, proliferation, and apoptosis. Tescalcin is a calcium-binding protein containing an EF-hand domain, enabling it to interact with calcium-dependent signaling pathways. It is notably involved in modulating the ERK/MAPK signaling cascade, influencing cell cycle progression and tissue development. Studies highlight its expression in various tissues, including the heart, kidneys, and hematopoietic cells, with critical roles in megakaryocyte differentiation and cardiac hypertrophy.

Dysregulation of Tescalcin has been linked to cancers, such as colorectal carcinoma and leukemia, where it may act as an oncogene or tumor suppressor depending on context. In research, TESC antibodies are essential tools for detecting Tescalcin expression via techniques like Western blotting, immunohistochemistry, and immunofluorescence, aiding investigations into its mechanistic roles and disease associations. Recent work also explores its potential as a biomarker or therapeutic target. However, functional studies remain ongoing to fully elucidate its interactions and regulatory networks in both physiological and pathological states.