ALDH2抗体—艾普蒂

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     Western blot analysis usingALDH2 mouse mAb against HepG2(1), A549 (2) cell lysatell and Rat liver(3), Mouse liver (4), Mouse brain (5)tissue lysate.    

  
  

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     Western blot analysis using ALDH2 mouse mAb against mouse liver(1)Raw264.7(2)NIH/3T3(3)NRK(4)C2C12(5)C6(6)F9(7)COS-7(8)CHO3D10(9)cell lysate.    

  
  

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     Immunofluorescence analysis of HepG2 cells using ALDH2 mouse mAb (green). Blue: DRAQ5 fluorescentDNA dve. Red: Actin filaments havebeen labeled with Alexa Fluor-555phalloidin.    

  
  

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     Immunofluorescence analysis of NIH/3T3 cells using ALDH2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.    

  
  

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     Flow cvtometric analvsis ofHeLa cells using ALDH2 mouse mAb(green) and negative control (purple).    

  
  

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     Flow cytometric analysis of  NIH/3T3 cells using  ALDH2 mouse mAb (green) and negative control (red).    

  
  

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     Flow cytometric analysis of  PC-12 cells using  ALDH2 mouse mAb (green) and negative control (red).    

  
  

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     Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using ALDH2 mouse mAb with DAB staining.    

  
  

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     Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using ALDH2 mouse mAb with DAB staining.    

  
  

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     Immunohistochemical analysis of paraffin-embedded Mouse liver(A) Mouse kidney(B) using ALDH2 mouse mAb with DAB staining.    

  
  

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     Immunohistochemical analysis of paraffin-embedded Rat liver(A) Rat kidney(B) using ALDH2 mouse mAb with DAB staining.    

  
  

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     Immunohistochemical analysis of paraffin-embedded Rabbit liver(A) Rabbit kidney(B) using ALDH2 mouse mAb with DAB staining.    

  
  

**Background of ALDH2 Antibodies**

Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme critical for metabolizing toxic aldehydes, including acetaldehyde (a byproduct of alcohol metabolism) and reactive lipid peroxidation products. The *ALDH2* gene exhibits a common polymorphism (Glu504Lys, rs671) prevalent in East Asian populations, which significantly reduces enzyme activity. This variant is linked to alcohol flushing syndrome, increased cancer risk, and susceptibility to cardiovascular and neurodegenerative diseases.

ALDH2 antibodies are immunological tools designed to detect and quantify ALDH2 protein expression, localization, or functional alterations in research. These antibodies, often polyclonal or monoclonal, are validated for techniques like Western blotting, immunohistochemistry, and ELISA. They help investigate ALDH2's role in cellular detoxification, oxidative stress response, and disease mechanisms. For instance, studies use ALDH2 antibodies to explore its protective effects in ischemic heart injury, its association with cancer stem cells, or its dysfunction in Alzheimer’s disease.

Given ALDH2's clinical relevance, these antibodies are vital for translational research, enabling insights into genetic susceptibility, biomarker discovery, and therapeutic targeting. Specificity validation across species (human, mouse, rat) and applications in diverse sample types (tissues, cell lines) ensure their utility in both basic and clinical studies.