C17ORF53抗体—艾普蒂 新品

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     Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);    

  
  

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     Immunofluorescence analysis of HepG2 cells using C17ORF53 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.    

  
  

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     Flow cytometric analysis of Jurkat cells using C17ORF53 mouse mAb (green) and negative control (red).    

  
  

**Background of C17ORF53 Antibody**

C17ORF53 (Chromosome 17 Open Reading Frame 53), also known as CFAP53 or CILD44. is a protein-coding gene located on human chromosome 17q21.2. While its precise molecular function remains under investigation, studies suggest its potential involvement in ciliary assembly and motility, with mutations linked to primary ciliary dyskinesia (PCD), a genetic disorder affecting respiratory and reproductive systems. C17ORF53 antibodies are immunological tools designed to detect and study the expression, localization, and interactions of the C17ORF53 protein. These antibodies are typically produced in host organisms (e.g., rabbits or mice) using immunogenic peptides derived from conserved regions of the protein.

C17ORF53 antibodies are widely utilized in techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to investigate protein expression levels in tissues or cell lines. Their applications extend to research on ciliopathies, respiratory diseases, and cellular mechanisms underlying ciliary dysfunction. Validation data, including specificity (e.g., knockout-validated) and cross-reactivity, are critical for ensuring reliability in experimental settings. As research advances, C17ORF53 antibodies continue to support efforts in elucidating the gene’s role in health and disease.