基本信息 产品详情 公司简介 推荐产品
  • 首页
  • 个人中心
  • 委托采购
  • 采购清单
网站主页 化工产品目录 生物化工 抗体 一抗 多抗 PARK7 antibody PARK7抗体
  • PARK7抗体—艾普蒂
  • PARK7抗体—艾普蒂
  • PARK7抗体—艾普蒂

1/3

PARK7抗体—艾普蒂

Mouse Monoclonal PARK7 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
上海 更新日期：2025-05-16

上海切尔齐生物科技有限公司

VIP1年
联系人：周经理
电话：027-19371278702拨打
手机：18008634902 拨打
邮箱：ruihening88@163.com

产品详情:

中文名称：
PARK7抗体
英文名称：
Mouse Monoclonal PARK7 Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 1509 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Mouse
偶联物：
无
靶点：
PARK7

验证与应用

应用及物种
WB1/500 - 1/2000 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/200 - 1/1000 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM1/200 - 1/400 Human,Mouse,Rat
Elisa1/10000 Human,Mouse,Rat
   

产品详情

AliasesDJ1; DJ-1; GATD2; HEL-S-67p
Entrez GeneID11315
clone2B1G12
WB Predicted band size19.8kDa
Host/IsotypeMouse IgG1
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenPurified recombinant fragment of human PARK7 (AA: 1-189) expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide

+ +

  •  

     

       Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)    


  •  

     

       Western blot analysis using PARK7 mouse mAb against A549 (1), A431 (2),K562 (3),Hela(4), SH-SY5Y (5) and SW480 (6) cell lysate.    


  •  

     

       Flow cytometric analysis of HepG2 cells using PARK7 mouse mAb (green) and negative control (red).    


  •  

     

       Immunohistochemical analysis of paraffin-embedded human brain tissues using PARK7 mouse mAb with DAB staining.    


  •  

     

       Immunohistochemical analysis of paraffin-embedded human prostate cancer tissues using PARK7 mouse mAb with DAB staining.    


           

参考文献

以下是关于PARK7(DJ-1)抗体的3篇参考文献的简要概括(文献信息为示例性整理，具体内容需参考真实文献)：

1. **文献名称**：*Development and validation of a novel PARK7/DJ-1 monoclonal antibody for neurodegenerative disease research*

**作者**：Smith A, et al.

**摘要**：本研究报道了一种高特异性PARK7单克隆抗体的开发，验证了其在人脑组织和帕金森病模型中的检测效果，证实其可用于Western blot和免疫组化分析。

2. **文献名称**：*DJ-1 antibody-based detection of oxidative stress markers in Alzheimer's and Parkinson's disease models*

**作者**：Chen L, et al.

**摘要**：利用PARK7抗体探究DJ-1蛋白在神经退行性疾病中的氧化应激保护作用，发现其在阿尔茨海默病和帕金森病模型中表达水平异常，与疾病进程相关。

3. **文献名称**：*PARK7 interacts with α-synuclein in vivo: Evidence from co-immunoprecipitation assays using specific antibodies*

**作者**：Yamamoto K, et al.

**摘要**：通过PARK7抗体进行免疫共沉淀实验，揭示了DJ-1与α-突触核蛋白的相互作用，提示其在帕金森病病理蛋白聚集调控中的潜在功能。

4. **文献名称**：*Evaluation of serum DJ-1 as a biomarker using a novel ELISA system with dual antibody recognition*

**作者**：Zhang R, et al.

**摘要**：开发了一种基于双PARK7抗体的ELISA检测方法，评估了血清DJ-1作为帕金森病早期诊断生物标志物的敏感性和特异性。

注：以上文献标题和内容为示例性总结，实际文献需通过PubMed等平台检索确认。

       

背景信息

PARK7. also known as DJ-1. is a multifunctional protein encoded by the *PARK7* gene, initially linked to early-onset Parkinson’s disease (PD). It plays roles in antioxidative stress, mitochondrial regulation, and cellular homeostasis. Mutations in *PARK7* are associated with autosomal recessive PD, driving research into its pathological mechanisms. PARK7 antibodies are essential tools for studying this protein’s expression, localization, and function in both healthy and diseased states.

These antibodies enable detection of PARK7 in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. Researchers use them to investigate PARK7’s interaction with pathways implicated in neurodegeneration, such as oxidative damage mitigation and α-synuclein aggregation. PARK7 antibodies also help explore its potential roles beyond PD, including cancer, metabolic disorders, and inflammation.

Commercially available PARK7 antibodies are typically raised against specific epitopes, with validation in human or model organism tissues. Challenges include ensuring specificity due to structural similarities with other proteins. Recent studies highlight PARK7’s dual role as a biomarker and therapeutic target, emphasizing the need for reliable antibodies to advance diagnostic and therapeutic strategies for PD and related conditions.

       
PARK7抗体;PARK7;PARK7 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业，

成立日期 (2年)
注册资本 20万人民币
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 抗体,蛋白组学,细胞生物学

PARK7抗体相关厂家报价

内容声明
official 进入官方账号
拨打电话 立即询价