THAP9抗体

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     The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P12282(THAP9 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

The THAP9 antibody is designed to target the THAP domain-containing protein 9 (THAP9), a member of the THAP family of proteins characterized by a zinc-dependent DNA-binding domain. THAP9 is evolutionarily conserved and shares homology with the Hsmar1 transposase, suggesting potential roles in transcriptional regulation, chromatin remodeling, and mobilization of transposable elements. Studies indicate THAP9 may influence genomic stability, cell proliferation, and differentiation, with emerging links to cancer biology and neurological disorders. Its expression has been detected in various tissues, including the brain, testes, and certain tumors, though its precise physiological and pathological functions remain under investigation.

The THAP9 antibody is primarily used in research to detect and quantify THAP9 protein levels via techniques like Western blotting, immunohistochemistry, and immunofluorescence. It aids in elucidating THAP9’s interaction partners, subcellular localization, and regulatory mechanisms. Recent applications include exploring its involvement in DNA repair pathways, epigenetic modulation, and transposon silencing. Commercially available antibodies are typically validated for specificity and sensitivity, though batch variability can occur. As THAP9 gains attention for its dual roles in genome regulation and disease, this antibody serves as a critical tool for advancing studies in developmental biology, oncology, and neurobiology.