FAM186B抗体

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     The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P09957(FAM186B Antibody) at dilution 1/25. (Original magnification: ×200)    

  
  

**Background of FAM186B Antibody**

The FAM186B antibody is a research tool designed to target FAM186B (Family with sequence similarity 186 member B), a protein encoded by the *FAM186B* gene in humans. This gene, part of the FAM186 family, is poorly characterized but is thought to play roles in cellular processes such as proliferation, differentiation, or intracellular signaling. FAM186B’s exact biological function remains unclear, though studies suggest its potential involvement in cancer progression, particularly in colorectal and gastric cancers, where aberrant expression has been observed.

The FAM186B antibody is typically developed in hosts like rabbits or mice using immunogenic peptides or recombinant protein fragments. It is widely used in techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect FAM186B expression levels, subcellular localization, and tissue distribution. Researchers utilize this antibody to explore FAM186B’s role in disease mechanisms, biomarker potential, or interactions with other proteins.

Recent studies highlight FAM186B’s differential expression in tumors versus normal tissues, linking it to patient prognosis. However, limited functional data and validation studies necessitate further research to confirm its pathological relevance. Commercial FAM186B antibodies often require rigorous validation for specificity and reproducibility, emphasizing their role as critical, yet evolving, tools in molecular and cancer biology research.