MRPS24抗体

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     The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P09838(MRPS24 Antibody) at dilution 1/90. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P09838(MRPS24 Antibody) at dilution 1/90. (Original magnification: ×200)    

  
  

The MRPS24 antibody is a research tool designed to detect and study the mitochondrial ribosomal protein S24 (MRPS24), a key component of the small subunit (28S) of the mitochondrial ribosome. Mitochondrial ribosomes are essential for translating mitochondrial DNA-encoded mRNAs, which produce subunits of the oxidative phosphorylation (OXPHOS) complexes critical for cellular energy production. MRPS24. encoded by the nuclear genome, is imported into mitochondria and plays a structural or regulatory role in ribosomal assembly and protein synthesis.

Antibodies targeting MRPS24 are widely used in applications such as Western blotting, immunofluorescence, and immunohistochemistry to evaluate protein expression levels, subcellular localization, and mitochondrial function in various experimental models. Dysregulation of MRPS24 has been linked to mitochondrial disorders, metabolic diseases, and cancer, as impaired ribosomal function can disrupt OXPHOS and promote metabolic reprogramming.

Researchers also utilize MRPS24 antibodies to investigate mitochondrial dysfunction in neurodegenerative diseases, aging, and genetic syndromes caused by mutations in mitochondrial ribosomal proteins. Validated antibodies are critical for ensuring specificity, given the high homology among ribosomal proteins. Commercial MRPS24 antibodies are typically raised in rabbits or mice and tested for cross-reactivity across human, mouse, and rat tissues, supporting translational and mechanistic studies in both health and disease contexts.