C9orf116抗体

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     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P09807(C9orf116 Antibody) at dilution 1/55. (Original magnification: ×200)    

  
  

The C9orf116 antibody is a research tool designed to detect the protein encoded by the *C9orf116* gene (Chromosome 9 Open Reading Frame 116), a poorly characterized gene with limited functional information. This gene is conserved across vertebrates, suggesting potential biological importance, though its precise role remains unclear. Studies have linked C9orf116 to cellular processes such as protein synthesis, mitochondrial function, or stress responses, but these associations are often speculative and require further validation.

The C9orf116 antibody is primarily used in experimental settings, including Western blotting, immunofluorescence, and immunohistochemistry, to localize the protein within tissues or cells and assess its expression levels under varying conditions. Its utility is critical in exploratory research aiming to elucidate the gene’s function, particularly in disease contexts. For example, some studies have investigated C9orf116 expression in cancer or neurodegenerative disorders, though findings remain preliminary.

Commercially available C9orf116 antibodies are typically polyclonal or monoclonal, generated using peptide antigens derived from predicted protein sequences. However, specificity and reliability can vary, necessitating careful validation via controls like knockout cell lines. Despite its niche application, this antibody represents a key reagent for probing the enigmatic roles of C9orf116 in basic biology and disease mechanisms. Ongoing research may clarify its relevance as a biomarker or therapeutic target.