FADS3抗体

+ +

•  

   

     The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P09720(FADS3 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

•  

   

     The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P09720(FADS3 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

The FADS3 (Fatty Acid Desaturase 3) antibody is a tool used to study the FADS3 protein, a member of the fatty acid desaturase family involved in lipid metabolism. FADS3. encoded by the *FADS3* gene, is less characterized compared to its homologs FADS1 and FADS2. which catalyze the introduction of double bonds in polyunsaturated fatty acids (PUFAs) like omega-3 and omega-6 fatty acids. While FADS1/2 are well-studied in PUFA synthesis, FADS3's enzymatic activity and substrates remain unclear, though it is hypothesized to influence specialized lipid pathways, including sphingolipid metabolism or branched-chain fatty acid modification.

FADS3 antibodies are primarily used in research to detect protein expression, localization, and regulation in tissues, particularly in the brain, skin, and liver. Studies suggest FADS3 may play roles in neurodevelopment, epidermal barrier function, and lipid signaling. Its aberrant expression has been linked to metabolic disorders, cancer, and neurodegenerative diseases, though mechanistic insights are limited. Commercial FADS3 antibodies are typically validated for applications like Western blotting, immunohistochemistry, and immunofluorescence, enabling exploration of its tissue-specific roles. However, inconsistencies in antibody specificity and variability in reported molecular weights (~45-50 kDa) across studies highlight challenges in standardization. Ongoing research aims to clarify FADS3's biological significance and its potential as a therapeutic or diagnostic target.