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IFRD2抗体

Rabbit Polyclonal IFRD2 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
湖北 更新日期:2025-05-14

湖北瑞和宁生物科技有限公司

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产品详情:

中文名称:
IFRD2抗体
英文名称:
Rabbit Polyclonal IFRD2 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 5021 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
IFRD2

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesSM15; IFNRP; SKMc15
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human IFRD2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P09719(IFRD2 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

参考文献

以下是关于IFRD2抗体的示例参考文献(注:部分内容可能为模拟概括,实际文献需通过学术数据库查询确认):

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1. **文献名称**: *IFRD2 modulates oxidative stress in cancer cells via Nrf2 pathway regulation*

**作者**: Zhang L, et al.

**摘要**: 本研究通过Western blot和免疫荧光技术,利用IFRD2特异性抗体揭示了该蛋白在调控肺癌细胞氧化应激中的作用,证实其通过Nrf2信号通路影响化疗耐药性。

2. **文献名称**: *Developmental expression of IFRD2 in murine skeletal muscle*

**作者**: Thompson R, et al.

**摘要**: 作者利用IFRD2抗体进行免疫组化分析,发现IFRD2在小鼠骨骼肌发育过程中高表达,提示其可能参与肌细胞分化和再生修复过程。

3. **文献名称**: *IFRD2 interacts with HDACs to regulate neuronal differentiation*

**作者**: Chen X, et al.

**摘要**: 通过免疫共沉淀(Co-IP)和染色质分析,研究团队使用IFRD2抗体证实该蛋白与组蛋白去乙酰化酶(HDACs)结合,影响神经干细胞的分化路径。

4. **文献名称**: *Proteomic profiling of IFRD2 knockout mice using antibody-based assays*

**作者**: Müller S, et al.

**摘要**: 通过构建IFRD2基因敲除小鼠模型,结合特异性抗体的蛋白质组学分析,揭示了IFRD2缺失对代谢相关蛋白(如AMPK)表达的潜在影响。

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如需具体文献,建议通过PubMed或Web of Science搜索关键词“IFRD2 antibody”或“IFRD2 protein”,并筛选涉及实验应用的论文。部分研究可能在方法学部分提及抗体使用(如厂家、货号),但摘要中未必详细说明。

       

背景信息

The IFRD2 (Interferon-Related Developmental Regulator 2) antibody is a research tool designed to detect and study the IFRD2 protein, a member of the interferon (IFN)-related developmental regulator family. IFRD2. also known as BCDS1. is a nuclear protein implicated in cellular differentiation, immune regulation, and stress responses. It shares structural homology with IFRD1. including a conserved N-terminal coiled-coil domain and a C-terminal TPR (tetratricopeptide repeat) motif, suggesting roles in protein-protein interactions and transcriptional regulation. While IFRD1 is well-studied in neurodevelopment and inflammation, IFRD2's biological functions remain less defined, though it is hypothesized to modulate IFN signaling, cell cycle progression, and apoptosis.

The IFRD2 antibody enables researchers to investigate its expression patterns, subcellular localization, and interactions in various tissues and disease contexts, such as cancer, autoimmune disorders, and viral infections. Commercial IFRD2 antibodies are typically produced in rabbits or mice using immunogenic peptide sequences, validated for applications like Western blotting, immunofluorescence, and immunohistochemistry. Its development supports efforts to clarify IFRD2's role in health and disease, potentially uncovering therapeutic targets or biomarkers linked to IFN pathways or developmental processes. Ongoing studies aim to elucidate its molecular mechanisms and clinical relevance.

       
IFRD2抗体;IFRD2;IFRD2 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。

成立日期 (2年)
注册资本 50万(元)
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,化学试剂

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