MBOAT7抗体

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     The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P09666(MBOAT7 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P09666(MBOAT7 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

**Background of MBOAT7 Antibodies**

MBOAT7 (Membrane-Bound O-Acyltransferase Family Member 7), also known as lysophosphatidylinositol acyltransferase 1 (LPIAT1), is an enzyme encoded by the *MBOAT7* gene. It plays a critical role in phospholipid remodeling, particularly in transferring unsaturated fatty acids to lysophosphatidylinositol (LPI) to form phosphatidylinositol (PI), a key component of cellular membranes and signaling pathways. Dysregulation of MBOAT7 has been linked to metabolic disorders, liver diseases, neurodegenerative conditions, and cancer.

Antibodies targeting MBOAT7 are essential tools for studying its expression, localization, and function. They enable detection and quantification of the protein in various experimental models, including Western blotting, immunohistochemistry, and immunofluorescence. MBOAT7 antibodies have been pivotal in elucidating its role in lipid metabolism, inflammation, and disease progression. For example, reduced MBOAT7 activity is associated with non-alcoholic fatty liver disease (NAFLD), while genetic variants are implicated in psychiatric disorders.

Recent research also highlights MBOAT7's potential as a therapeutic target or biomarker. High-quality, validated antibodies are crucial to ensure specificity and reproducibility in these studies. Challenges include distinguishing MBOAT7 from other acyltransferases due to structural similarities, underscoring the need for well-characterized antibodies. Overall, MBOAT7 antibodies continue to advance understanding of lipid biology and its intersection with human health.