ARMCX1抗体

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07894(ARMCX1 Antibody) at dilution 1/40. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P07894(ARMCX1 Antibody) at dilution 1/40. (Original magnification: ×200)    

  
  

The ARMCX1 antibody is a tool used to detect the ARMCX1 protein, a member of the ARMCX family (Armadillo repeat-containing X-linked proteins). ARMCX1 contains multiple Armadillo (ARM) repeats, which are evolutionarily conserved structural motifs involved in protein-protein interactions and cellular processes. This protein is localized to mitochondria and is thought to play roles in mitochondrial transport, dynamics, or network organization, though its precise molecular mechanisms remain under investigation. ARMCX1 is broadly expressed in human tissues, with higher levels observed in the nervous system, suggesting potential relevance in neural development or function.

Studies link ARMCX1 to cellular processes such as apoptosis, cell migration, and tumor suppression. For instance, reduced ARMCX1 expression has been associated with enhanced cancer cell invasiveness in certain malignancies, including glioblastoma. The ARMCX1 antibody enables researchers to study its expression patterns, subcellular localization, and interactions via techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). It has been particularly useful in exploring ARMCX1's role in mitochondrial dysfunction-related diseases, such as neurodegenerative disorders, and its regulatory effects on signaling pathways like Wnt/β-catenin. However, challenges persist in fully elucidating its physiological substrates and disease-specific implications, necessitating further research.