ANKMY1抗体

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     The image is immunohistochemistry of paraffin-embedded Human brain tissue using P07848(ANKMY1 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P07848(ANKMY1 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

The ANKMY1 antibody is a research tool used to detect ANKMY1 (Ankyrin Repeat and MYND Domain Containing 1), a protein encoded by the ANKMY1 gene in humans. This protein contains ankyrin repeat domains, which are known to mediate protein-protein interactions, and a MYND domain, typically involved in transcriptional regulation through chromatin remodeling. While the full functional role of ANKMY1 remains under investigation, studies suggest its potential involvement in cellular processes such as DNA damage response, cell cycle regulation, and neural development. It has been linked to interactions with proteins like DYRK1A (dual-specificity tyrosine phosphorylation-regulated kinase 1A), implicating possible roles in neurodevelopmental pathways or disorders.

ANKMY1 antibodies are primarily utilized in molecular biology and biomedical research to study the expression, localization, and functional mechanisms of ANKMY1 in various tissues and disease models. These antibodies are validated for applications such as Western blotting, immunofluorescence, and immunohistochemistry. Emerging evidence highlights ANKMY1's potential relevance in cancer biology, with altered expression observed in certain malignancies, though its exact role as an oncogene or tumor suppressor remains unclear. Commercial ANKMY1 antibodies are available from multiple suppliers, often developed using immunogens targeting specific epitopes within the protein's conserved regions. Ongoing research aims to clarify its physiological and pathological significance, particularly in contexts like neurodevelopment, genomic stability, and disease progression.