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CAPG抗体

Rabbit Polyclonal CAPG Antibody
询价 20μl 起订
50μl 起订
100μl 起订
湖北 更新日期：2025-05-13

湖北瑞和宁生物科技有限公司

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产品详情:

中文名称：
CAPG抗体
英文名称：
Rabbit Polyclonal CAPG Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 3729 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
CAPG

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesMCP; AFCP
WB Predicted band size38 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human CAPG
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Mouse lung tissue, human fetal lung tissue, hela cells, Primary antibody: P07757(CAPG Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P07757(CAPG Antibody) at dilution 1/35. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P07757(CAPG Antibody) at dilution 1/35. (Original magnification: ×200)    


           

参考文献

以下是关于CAPG抗体的3篇参考文献示例(注：以下内容为模拟生成，仅供参考)：

1. **文献名称**: "CAPG as a Biomarker in Triple-Negative Breast Cancer: Immunohistochemical Analysis Using a Novel Monoclonal Antibody"

**作者**: Smith, J.R., et al.

**摘要**: 该研究开发了一种新型抗CAPG单克隆抗体，并通过免疫组化分析发现CAPG在三阴性乳腺癌组织中高表达，与肿瘤转移和不良预后显著相关。结果表明CAPG可能作为潜在的治疗靶点或诊断标志物。

2. **文献名称**: "Autoantibodies to Cytoskeletal Protein CAPG in Rheumatoid Arthritis: Clinical Associations and Pathogenic Role"

**作者**: Tanaka, M., et al.

**摘要**: 研究检测了类风湿性关节炎(RA)患者血清中的CAPG自身抗体水平，发现其与疾病活动度和关节破坏程度呈正相关。实验表明CAPG抗体可能通过激活NF-κB通路加剧炎症反应，提示其在RA发病机制中的作用。

3. **文献名称**: "Development of a High-Sensitivity ELISA for CAPG Detection in Pancreatic Cancer Serum Samples"

**作者**: Wang, L., et al.

**摘要**: 该团队利用CAPG多克隆抗体建立了一种高灵敏度ELISA检测方法，证实胰腺癌患者血清CAPG水平显著高于健康对照组，且与肿瘤分期相关。该方法为无创诊断胰腺癌提供了新策略。

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*注：以上文献信息为示例性模拟，实际研究中请通过学术数据库(如PubMed、Web of Science)以关键词“CAPG antibody”“CAPG biomarker”等检索最新文献。*

       

背景信息

CAPG (macrophage-capping protein) is an actin-binding protein belonging to the gelsolin superfamily, primarily involved in regulating actin filament dynamics. It modulates cell membrane architecture, motility, and intracellular trafficking by capping the barbed ends of actin filaments, thereby stabilizing cytoskeletal structures. CAPG is expressed in various tissues, with notable roles in immune cells (e.g., macrophages, neutrophils) and cancer cells. Its dual localization in the cytoplasm and nucleus suggests additional functions in transcriptional regulation and chromatin remodeling.

CAPG antibodies are widely used in research to investigate its expression patterns and mechanistic roles. Overexpression of CAPG has been linked to tumor progression, metastasis, and poor prognosis in cancers such as breast, prostate, and colorectal cancer, making it a potential biomarker or therapeutic target. In immunology, CAPG antibodies help study its involvement in inflammatory responses and phagocytosis.

Commercially available CAPG antibodies are developed for techniques like Western blotting, immunohistochemistry, and immunofluorescence. However, specificity validation remains crucial due to structural similarities within the gelsolin family. Recent studies also explore CAPG's interaction with viral pathogens and its role in neurodegenerative diseases, expanding its relevance in biomedical research.

       
CAPG抗体;CAPG;CAPG Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力， 拥有完整、科学、质量管理体系。并不断致力于技术创新，产品创新和管理创新，赢得了国内外广大用户的信任。

成立日期 (2年)
注册资本 50万(元)
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,化学试剂

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