SYT6抗体 新品

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     The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P07629(SYT6 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P07629(SYT6 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

The Synaptotagmin 6 (SYT6) antibody is a tool used to detect and study SYT6. a member of the synaptotagmin family of calcium-binding proteins. SYT6 is primarily associated with intracellular vesicle trafficking and membrane fusion processes, particularly in secretory pathways. Unlike other synaptotagmins (e.g., SYT1) that regulate synaptic vesicle exocytosis in neurons, SYT6 is broadly expressed in endocrine cells, pancreatic β-cells, and certain brain regions, suggesting roles in hormone secretion, insulin release, and specialized neurosecretory functions.

SYT6 antibodies are commonly employed in research to investigate its localization, expression levels, and interaction partners using techniques like Western blotting, immunofluorescence, and immunohistochemistry. Studies have linked SYT6 to glucose-stimulated insulin secretion, lysosomal exocytosis, and cellular stress responses. Its involvement in diseases such as diabetes, neurodegenerative disorders, and cancer has spurred interest in understanding its molecular mechanisms.

These antibodies are typically raised in hosts like rabbits or mice, targeting specific epitopes within SYT6's conserved domains. Validation often includes knockout cell lines or tissue controls to ensure specificity. Research using SYT6 antibodies continues to clarify its dual roles in membrane repair and regulated secretion, highlighting its potential as a therapeutic target or biomarker in metabolic and neurological pathologies.