SYT5抗体

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human cerebrum tissue, PC3 cell lysates, Primary antibody: P07628(SYT5 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P07628(SYT5 Antibody) at dilution 1/60. (Original magnification: ×200)    

  
  

Synaptotagmin 5 (SYT5) is a member of the synaptotagmin family, a group of membrane-trafficking proteins characterized by tandem C2 domains and a single transmembrane region. Primarily expressed in neuronal and neuroendocrine tissues, SYT5 is implicated in regulating synaptic vesicle exocytosis, calcium-dependent neurotransmitter release, and intracellular membrane fusion events. Unlike its well-studied homologs SYT1 and SYT2. SYT5 exhibits distinct subcellular localization and functional roles, potentially influencing secretory pathways in specialized cell types or under specific physiological conditions.

SYT5 antibodies are essential tools for investigating its expression, localization, and molecular interactions. These antibodies are commonly used in techniques like Western blotting, immunohistochemistry, and immunoprecipitation to study SYT5's involvement in neurological processes, endocrine signaling, and diseases such as Parkinson's or cancer. Due to structural similarities among synaptotagmin isoforms, rigorous validation (e.g., knockout controls) is critical to ensure antibody specificity. Recent studies also explore SYT5's role in non-neuronal contexts, including immune regulation and insulin secretion, broadening its biomedical relevance. Reliable SYT5 antibodies thus support advancing research into cellular communication mechanisms and therapeutic targeting of trafficking-related disorders.