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LGALS2抗体新品

Rabbit Polyclonal LGALS2 Antibody

询价 20μl 起订

50μl 起订

100μl 起订

湖北更新日期：2025-05-13

湖北瑞和宁生物科技有限公司

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电话：027-19371278702拨打

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邮箱：19384116026@163.com

产品详情:

中文名称：: LGALS2抗体

英文名称：: Rabbit Polyclonal LGALS2 Antibody

品牌：: 艾普蒂

产地：: 武汉

保存条件：: Stored at -20°C for 3471 year. Avoid repeated freeze / thaw cycles.

产品类别：: 抗体

重组：: 否

应用：: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA

种属反应性：: Human,Mouse,Rat

宿主：: Rabbit

偶联物：: 无

靶点：: LGALS2

验证与应用

应用及物种

WB	1/500-1/2000	Human,Mouse,Rat
IF	咨询技术	Human,Mouse,Rat
IHC	1/50-1/100	Human,Mouse,Rat
ICC	技术咨询	Human,Mouse,Rat
FCM	咨询技术	Human,Mouse,Rat
Elisa	1/5000-1/10000	Human,Mouse,Rat

产品详情

Aliases	HL14
WB Predicted band size	15 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human LGALS2
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal intestines tissue and Mouse stomach tissue lysates, Primary antibody: P07310(LGALS2 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07310(LGALS2 Antibody) at dilution 1/40. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P07310(LGALS2 Antibody) at dilution 1/40. (Original magnification: ×200)

参考文献

以下是3篇涉及LGALS2(galectin-2)抗体的相关文献摘要：

1. **文献名称**: *"Galectin-2 modulates immune responses by regulating T-cell apoptosis"*

**作者**: Sato S, et al.

**摘要**: 本研究利用抗LGALS2抗体探究galectin-2在T细胞凋亡中的作用，发现其通过结合CD29(β1整合素)调控T细胞存活，影响炎症反应及自身免疫疾病发展。

2. **文献名称**: *"LGALS2 antibody inhibits atherosclerosis by targeting macrophage polarization"*

**作者**: Chen L, et al.

**摘要**: 通过抗LGALS2抗体阻断galectin-2功能，发现其可抑制巨噬细胞向促炎表型极化，减少动脉粥样硬化斑块形成，为心血管疾病治疗提供潜在靶点。

3. **文献名称**: *"Galectin-2 as a biomarker for inflammatory bowel disease: A monoclonal antibody-based detection approach"*

**作者**: Kimura H, et al.

**摘要**: 研究开发了高特异性抗LGALS2单克隆抗体，证实galectin-2在炎症性肠病患者血清中显著升高，提示其作为疾病诊断生物标志物的潜力。

4. **文献名称**: *"Antibody-mediated targeting of galectin-2 in cancer immunotherapy"*

**作者**: Wang Y, et al.

**摘要**: 利用抗LGALS2抗体阻断galectin-2与肿瘤微环境中免疫细胞的相互作用，增强抗肿瘤免疫应答，为癌症免疫治疗提供新策略。

(注：上述文献为示例性内容，实际文献需通过PubMed或Google Scholar检索关键词“LGALS2 antibody”、“galectin-2 antibody”获取。)

背景信息

**Background of LGALS2 Antibody**

The LGALS2 antibody targets the protein galectin-2. encoded by the *LGALS2* gene, a member of the galectin family known for binding β-galactoside sugars via conserved carbohydrate recognition domains. Galectin-2 is a small, homodimeric lectin expressed in various tissues, including the gastrointestinal tract, immune cells, and vascular endothelium. It plays roles in inflammation, apoptosis, and immune regulation by interacting with ligands such as lymphotoxin-α, influencing pathways like NF-κB signaling.

Research highlights LGALS2's association with cardiovascular diseases, particularly myocardial infarction, where specific polymorphisms may modulate disease risk. It is also implicated in autoimmune disorders and cancer progression, potentially affecting tumor immunity and metastasis.

LGALS2 antibodies are essential tools for detecting galectin-2 expression and localization in experimental models, using techniques like Western blotting, immunohistochemistry, and flow cytometry. These antibodies aid in studying galectin-2's functional mechanisms, its interaction with cellular components, and its diagnostic or therapeutic potential. Commercial LGALS2 antibodies are typically validated for specificity and cross-reactivity across species (e.g., human, mouse), supporting translational research in disease biomarkers and molecular pathways.

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公司简介

湖北瑞和宁生物科技有限公司研究创新能力，拥有完整、科学、质量管理体系。并不断致力于技术创新，产品创新和管理创新，赢得了国内外广大用户的信任。

成立日期	(2年)
注册资本	50万(元)
员工人数	1-10人
年营业额	￥ 100万以内
经营模式	贸易,工厂,试剂,定制,服务
主营行业	中间体,化学试剂