RDX抗体

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     Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Hela cells, human brain tissue, 293T cells, human hepatocellular carcinoma tissue, NIH/3T3 cells, Primary antibody: P07287(RDX Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P07287(RDX Antibody) at dilution 1/60. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P07287(RDX Antibody) at dilution 1/60. (Original magnification: ×200)    

  
  

RDX (Research Department eXplosive), also known as cyclotrimethylenetrinitramine, is a nitroamine-based explosive widely used in military and industrial applications. Due to its environmental persistence and toxicity, detecting RDX contamination in soil, water, and biological samples has become critical for environmental monitoring and public health. Traditional analytical methods like chromatography are precise but require specialized equipment and trained personnel, limiting on-site applications.

RDX antibodies, developed through immunochemical techniques, offer a rapid, cost-effective alternative for field-deployable detection. These antibodies are typically produced by immunizing animals (e.g., rabbits or mice) with RDX derivatives conjugated to carrier proteins, as RDX itself is too small to elicit an immune response alone. Monoclonal or polyclonal antibodies generated against RDX exhibit specific binding to the compound or its metabolites, enabling sensitive detection at trace levels (parts-per-billion range).

Applications include enzyme-linked immunosorbent assays (ELISAs), lateral flow immunoassays, and biosensors for real-time monitoring. Challenges remain in minimizing cross-reactivity with structurally similar compounds like HMX or degradation products. Recent advances in recombinant antibody engineering and nanotechnology-enhanced platforms aim to improve specificity and detection limits. RDX antibodies have become essential tools for environmental agencies, military operations, and forensic investigations to address contamination risks and ensure regulatory compliance.