CAMK1G抗体

+ +

•  

   

     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: P07148(CAMK1G Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1MIN    

  
  

•  

   

     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07148(CAMK1G Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

•  

   

     The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P07148(CAMK1G Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

The CAMK1G antibody is a research tool designed to detect and quantify the calcium/calmodulin-dependent protein kinase 1G (CAMK1G), a member of the CAMK serine/threonine kinase family. CAMK1G is part of the CAMK1 subfamily, which includes kinases activated by calcium/calmodulin signaling. This enzyme plays a role in regulating cellular processes such as transcriptional activation, cell cycle progression, and hormone secretion by phosphorylating downstream targets. Structurally, CAMK1G contains a catalytic domain, an autoinhibitory regulatory domain, and a C-terminal extension that may influence subcellular localization and substrate specificity.

Expressed predominantly in the brain, testis, and endocrine tissues, CAMK1G is implicated in neural development, synaptic plasticity, and endocrine functions. Studies suggest its involvement in pathways linking calcium signaling to gene expression, often interacting with upstream activators like CAMKK and calmodulin. Dysregulation of CAMK1G has been explored in neurological disorders and metabolic syndromes, though its exact pathophysiological roles remain under investigation.

The CAMK1G antibody is widely used in techniques such as Western blotting, immunohistochemistry, and immunofluorescence to study protein expression, localization, and activity in cellular or tissue samples. Researchers rely on its specificity to explore CAMK1G's interactions, activation mechanisms, and relevance in disease models. Validated antibodies are critical for distinguishing CAMK1G from homologous kinases, ensuring accuracy in experimental data. As calcium signaling pathways are central to numerous physiological and pathological processes, CAMK1G antibodies serve as essential tools for advancing understanding of cellular signaling networks.