UBTD1抗体

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A375 and Raji cell lysates, Primary antibody: P05477(UBTD1 Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P05477(UBTD1 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

The UBTD1 (Ubiquitin Domain-Containing Protein 1) antibody is a tool used to study the UBTD1 protein, which plays a role in ubiquitination—a critical post-translational modification process regulating protein stability, localization, and interactions. UBTD1 contains a conserved ubiquitin-associated (UBA) domain, suggesting its involvement in ubiquitin-dependent pathways, though its precise mechanisms remain under investigation. Research indicates UBTD1 may influence cell cycle progression, apoptosis, and DNA damage response, potentially acting as a scaffold or modulator in ubiquitin ligase complexes. Dysregulation of UBTD1 has been linked to cancers and neurodegenerative disorders, highlighting its biomedical relevance.

The UBTD1 antibody is primarily utilized in techniques like Western blotting, immunofluorescence, and immunoprecipitation to detect UBTD1 expression, subcellular localization, and interaction partners. It aids in elucidating UBTD1’s role in cellular processes and disease contexts. Commercially available antibodies are typically raised against specific epitopes, such as recombinant fragments or synthetic peptides, with validation data confirming specificity via knockout controls or siRNA knockdown. Researchers employ this antibody to explore UBTD1’s functional dynamics, including its response to stress signals or therapeutic agents. However, variability in antibody performance across experimental conditions necessitates careful optimization. Ongoing studies aim to clarify UBTD1’s regulatory networks, emphasizing the antibody’s value in advancing ubiquitin-proteasome system research.