SLC5A10抗体

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     The image is immunohistochemistry of paraffin-embedded Human brain tissue using P05315(SLC5A10 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P05315(SLC5A10 Antibody) at dilution 1/30. (Original magnification: ×200)    

  
  

The SLC5A10 antibody is a tool used to detect and study the solute carrier family 5 member 10 (SLC5A10), a sodium-dependent glucose transporter protein encoded by the *SLC5A10* gene. This transmembrane protein belongs to the SLC5/NAS (sodium-dependent nutrient transporter) family, which facilitates the active transport of glucose, vitamins, and other solutes across cell membranes using sodium gradients. SLC5A10 is primarily expressed in the kidneys and intestines, where it plays a role in reabsorbing glucose and maintaining metabolic homeostasis. Structurally, it features 12 transmembrane domains, characteristic of SLC5 transporters.

Research on SLC5A10 has focused on its potential involvement in glucose metabolism, renal function, and metabolic disorders like diabetes. Antibodies targeting SLC5A10 are essential for elucidating its expression patterns, cellular localization, and interactions in physiological and pathological contexts. These antibodies, often developed in rabbit or mouse models using immunogenic peptide fragments, are validated for techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Recent studies also explore SLC5A10’s role in cancer and rare genetic diseases, highlighting its broader biomedical relevance. However, challenges remain in standardizing antibody specificity due to protein homology within the SLC5 family. Overall, SLC5A10 antibodies are critical for advancing understanding of sodium-coupled transport mechanisms and their implications in health and disease.