SLC43A2抗体

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human normal stomach tissue, Primary antibody: P05311(SLC43A2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    

  
  

The solute carrier family 43 member 2 (SLC43A2) is a transmembrane protein encoded by the SLC43A2 gene, primarily involved in neutral amino acid transport, particularly phenylalanine. It plays a role in cellular nutrient sensing, immune regulation, and metabolic homeostasis. SLC43A2 is highly expressed in immune cells, such as T lymphocytes, and has been implicated in modulating T-cell function and immune responses. Recent studies suggest its potential involvement in cancer progression, as altered expression may influence tumor microenvironment interactions and amino acid availability critical for cell proliferation.

SLC43A2 antibodies are immunological tools designed to detect and quantify the presence of this protein in various experimental models. These antibodies are widely used in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to study SLC43A2's expression patterns, subcellular localization, and functional roles. Polyclonal and monoclonal variants are available, often generated against specific epitopes of the human or murine SLC43A2 protein. Validation typically includes knockout cell line controls to confirm specificity.

Research applications span cancer biology, immunometabolism, and neurological disorders, with particular interest in how SLC43A2-mediated amino acid transport impacts immune cell activation and tumor immune evasion. Its emerging role in cancer immunotherapy contexts has amplified the need for reliable SLC43A2 antibodies to explore therapeutic targeting potential.