SLC16A10抗体

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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse pancreas tissue lysate, Primary antibody: P05292(SLC16A10 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 3 minutes    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P05292(SLC16A10 Antibody) at dilution 1/25. (Original magnification: ×200)    

  
  

The solute carrier family 16 member 10 (SLC16A10), also known as T-type amino acid transporter 1 (TAT1), is a transmembrane protein that facilitates the transport of aromatic amino acids, including tryptophan, tyrosine, and phenylalanine. It belongs to the monocarboxylate transporter (MCT) family and functions as a proton-coupled symporter, playing a role in cellular nutrient uptake and metabolic regulation. SLC16A10 is expressed in various tissues, including the kidney, liver, intestine, and brain, where it contributes to amino acid homeostasis and interorgan metabolic communication.

Antibodies targeting SLC16A10 are critical tools for investigating its expression, localization, and functional roles in physiological and pathological contexts. Research has linked SLC16A10 to cancer progression, as tumor cells often upregulate amino acid transporters to meet increased metabolic demands. Studies also suggest its involvement in neurological disorders and metabolic diseases, such as diabetes, due to its impact on neurotransmitter synthesis and insulin signaling pathways.

These antibodies are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to validate protein levels in disease models or genetic knockouts. Additionally, they aid in exploring SLC16A10's interaction with signaling pathways like mTOR, which regulates cell growth in response to nutrient availability. Reliable SLC16A10 antibodies are essential for advancing research into targeted therapies and diagnostic biomarkers for diseases associated with amino acid dysregulation.