RAB6C抗体

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     The image is immunohistochemistry of paraffin-embedded Human brain tissue using P05201(RAB6C Antibody) at dilution 1/45. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P05201(RAB6C Antibody) at dilution 1/45. (Original magnification: ×200)    

  
  

The RAB6C antibody is a tool used to detect and study the RAB6C protein, a member of the RAB GTPase family involved in intracellular vesicle trafficking. RAB6C, part of the RAB6 subfamily (alongside RAB6A and RAB6B), plays a role in regulating Golgi-to-ER (endoplasmic reticulum) retrograde transport, secretory pathways, and membrane trafficking. While RAB6A is well-characterized, RAB6C remains less studied, though it shares structural homology and partially overlaps in function with RAB6A. RAB6C is implicated in maintaining Golgi integrity, modulating cargo sorting, and interacting with molecular motors for vesicle movement.

Antibodies targeting RAB6C enable researchers to investigate its expression, localization, and functional dynamics in various cell types and tissues. These antibodies are critical for techniques like Western blotting, immunofluorescence, and immunohistochemistry, aiding in the exploration of RAB6C’s role in physiological processes and diseases. Emerging studies suggest RAB6C dysregulation may link to cancer progression, neurological disorders, or genetic conditions, though its specific mechanisms remain under investigation. As RAB6C is expressed in a tissue-specific manner, its antibody also helps identify expression patterns in normal versus pathological states. Commercial RAB6C antibodies are typically developed in hosts like rabbits or mice, validated for specificity against conserved epitopes. Continued research using these antibodies may clarify RAB6C’s distinct contributions to cellular trafficking networks and disease pathways.