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  • EID3抗体
  • EID3抗体

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EID3抗体

Rabbit Polyclonal EID3 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
湖北 更新日期：2025-05-12

湖北瑞和宁生物科技有限公司

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联系人：周经理
电话：027-19371278702拨打
手机：18008634902 拨打
邮箱：19384116026@163.com

产品详情:

中文名称：
EID3抗体
英文名称：
Rabbit Polyclonal EID3 Antibody
品牌：
艾普蒂
产地：
武汉
保存条件：
Stored at -20°C for 2654 year. Avoid repeated freeze / thaw cycles.
产品类别：
抗体
重组：
否
应用：
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性：
Human,Mouse,Rat
宿主：
Rabbit
偶联物：
无
靶点：
EID3

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

产品详情

AliasesNS4EB; NSE4B; NSMCE4B
WB Predicted band size38 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human EID3
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse kidney tissue, Primary antibody: P04841(EID3 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P04841(EID3 Antibody) at dilution 1/15. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P04841(EID3 Antibody) at dilution 1/15. (Original magnification: ×200)    


           

参考文献

以下是关于EID3抗体的虚构参考文献示例(仅供格式参考，内容非真实文献)：

1. **"EID3 regulates chromatin remodeling in breast cancer via histone acetylation"**

- **作者**: Feng Y, et al.

- **摘要**: 本研究利用EID3特异性抗体，通过ChIP-seq技术揭示EID3通过抑制组蛋白乙酰转移酶EP300.调控乳腺癌细胞染色质重塑，促进肿瘤转移的分子机制。

2. **"Development and validation of a monoclonal antibody for EID3 in stem cell differentiation"**

- **作者**: Kim S, et al.

- **摘要**: 报道一种新型EID3单克隆抗体的开发与验证，证明其在人胚胎干细胞分化模型中可特异性识别EID3蛋白，并揭示EID3通过Wnt信号通路抑制分化的功能。

3. **"EID3-antibody-based profiling identifies its role in neuronal development"**

- **作者**: Patel R, et al.

- **摘要**: 通过免疫组织化学(IHC)结合EID3抗体，发现EID3在小鼠大脑皮层神经元发育中高表达，并参与调控神经前体细胞的增殖与迁移。

4. **"EID3 interacts with p53: Insights from co-immunoprecipitation studies"**

- **作者**: Zhang L, et al.

- **摘要**: 使用EID3抗体进行免疫共沉淀实验，证实EID3与肿瘤抑制因子p53直接结合，调控DNA损伤应答，为癌症治疗提供潜在靶点。

注：以上文献为模拟内容，实际研究中建议通过PubMed、Web of Science等数据库检索真实文献。

       

背景信息

The EID3 (EP300 Interacting Inhibitor of Differentiation 3) antibody is a tool used to study the EID3 protein, a member of the EID family known for regulating transcription by interacting with EP300—a histone acetyltransferase (HAT) critical for chromatin remodeling and gene expression. EID3 functions as an inhibitor by binding to EP300. suppressing its HAT activity, and modulating downstream transcriptional programs. This interaction plays roles in cellular processes like differentiation, proliferation, and apoptosis, with implications in cancer, stem cell biology, and developmental disorders.

The EID3 antibody enables detection and analysis of EID3 protein expression, localization, and interactions in various experimental setups, including Western blotting, immunoprecipitation, and immunofluorescence. Researchers employ it to explore EID3's regulatory mechanisms in diseases, particularly cancers where EP300/EID3 dysregulation may drive tumor progression. Studies also investigate its role in epigenetic modifications and cellular reprogramming.

Developed for specificity and sensitivity, the antibody supports both basic research and translational studies aiming to dissect EID3's contribution to signaling pathways or evaluate its potential as a therapeutic target. Its utility spans molecular biology, oncology, and epigenetics, offering insights into how EID3-mediated transcriptional repression influences health and disease.

       
EID3抗体;EID3;EID3 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力， 拥有完整、科学、质量管理体系。并不断致力于技术创新，产品创新和管理创新，赢得了国内外广大用户的信任。

成立日期 (2年)
注册资本 50万(元)
员工人数 1-10人
年营业额 ￥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,化学试剂

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