ZADH2抗体

The ZADH2 antibody is a research tool designed to target the ZADH2 protein, a member of the zinc-containing alcohol dehydrogenase (ADH) family. ZADH2. also referred to as alcohol dehydrogenase 2 (ADH2) in some species, is an enzyme involved in oxidizing alcohols to aldehydes or ketones, playing a critical role in cellular detoxification and metabolic pathways. This protein is particularly noted for its activity in ethanol metabolism, lipid oxidation, and retinol processing, making it relevant in studies of liver function, cancer biology, and oxidative stress responses. The ZADH2 antibody is typically produced in host species like rabbits or mice using immunogenic peptide sequences derived from conserved regions of the protein. It is widely utilized in techniques such as Western blotting, immunohistochemistry, and immunofluorescence to detect ZADH2 expression levels, localization, and post-translational modifications in tissues or cell lines. Researchers employ this antibody to explore ZADH2's involvement in diseases like hepatocellular carcinoma, metabolic disorders, and alcohol-related pathologies. Validated for specificity through knockout controls or siRNA knockdown experiments, the ZADH2 antibody serves as a key reagent in elucidating the enzyme's regulatory mechanisms and its potential as a therapeutic or diagnostic target.