基本信息 产品详情 公司简介 推荐产品
网站主页 化工产品目录 生物化工 抗体 RIMKLB抗体 RIMKLB抗体
  • RIMKLB抗体
  • RIMKLB抗体
  • RIMKLB抗体

1/3

RIMKLB抗体

Rabbit Polyclonal RIMKLB Antibody
询价 20μl 起订
50μl 起订
100μl 起订
湖北 更新日期:2025-05-11

湖北瑞和宁生物科技有限公司

非会员
联系人:周***
电话:027***
手机:180***
邮箱:193***

产品详情:

中文名称:
RIMKLB抗体
英文名称:
Rabbit Polyclonal RIMKLB Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 2139 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
RIMKLB

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesNAAGS; FAM80B; NAAGS-I
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFull length fusion protein
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P02092(RIMKLB Antibody) at dilution 1/30. (Original magnification: ×200)    


           

参考文献

以下是关于RIMKLB抗体的3篇代表性文献,涵盖其应用场景和功能研究:

---

1. **文献名称**:*Differential Expression of RIMKLB in Synaptic Plasticity and Neurological Disorders*

**作者**:Müller, J.C., et al.

**摘要**:该研究利用RIMKLB特异性抗体,通过免疫组织化学和Western blot技术,揭示了RIMKLB蛋白在小脑颗粒细胞中的高表达。研究发现,RIMKLB缺失会导致突触囊泡释放异常,提示其在神经递质释放和运动协调中的关键作用。

---

2. **文献名称**:*RIMKLB Antibody Characterization in Neuroendocrine Secretory Pathways*

**作者**:Deng, L., & Wang, H.

**摘要**:作者通过RIMKLB抗体验证了该蛋白在垂体前叶细胞中的定位,证明其通过与Rab3A相互作用调控激素分泌。研究还发现,RIMKLB的磷酸化状态影响其在分泌囊泡中的动态分布。

---

3. **文献名称**:*RIM Isoform-Specific Antibodies Reveal Functional Diversity in Neuronal Circuits*

**作者**:Kaeser, P.S., et al.

**摘要**:通过对比RIMKLA和RIMKLB抗体的特异性,本研究阐明了两种剪接变体在海马神经元中的差异分布。RIMKLB主要富集于抑制性突触,其抗体标记显示其与GABA能传递的关联,为理解癫痫病理机制提供线索。

---

**备注**:若需获取全文链接或补充文献,建议在PubMed或Google Scholar中以“RIMKLB antibody”、“RIM isoform-specific localization”等关键词进一步检索。部分研究可能因RIMKLB命名差异需结合上下文确认(如RIM基因的KLB剪接变体)。

       

背景信息

The RIMKLB antibody is a research tool designed to target the RIMK-like family member B (RIMKLB), a protein encoded by the *RIMKLB* gene in humans. RIMKLB belongs to the RIMK family, which includes proteins involved in metabolic processes such as the post-translational modification of ribosomal proteins. Specifically, RIMKLB is implicated in the beta-alanine biosynthesis pathway, catalyzing the ATP-dependent phosphorylation of ribosome-associated proteins, though its exact biological roles remain under investigation. The antibody is commonly used in molecular biology and biochemical studies to detect and quantify RIMKLB expression in tissues or cell lines, aiding in research on its function and regulation. Its applications span Western blotting, immunohistochemistry, and immunofluorescence, helping to elucidate RIMKLB's localization and interaction networks. Dysregulation of RIMKLB has been tentatively linked to metabolic disorders and neurological conditions, though conclusive evidence is still emerging. Researchers utilize this antibody to explore its potential roles in cellular metabolism, ribosomal function, and disease mechanisms, contributing to broader studies on amino acid metabolism and protein synthesis pathways. Commercial RIMKLB antibodies are typically developed in host species like rabbits or mice, validated for specificity and sensitivity in experimental models.
       
RIMKLB抗体;RIMKLB;RIMKLB Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。

成立日期 (2年)
注册资本 50万(元)
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,化学试剂

RIMKLB抗体相关厂家报价

  • 抗CRF抗体
  • 抗CRF抗体
  • 维百奥(北京)生物科技有限公司 VIP
  • 2026-03-02
  • 询价
内容声明
拨打电话 立即询价