ZFAND3抗体

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     Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: 293T cell lysate, Primary antibody: P02044(ZFAND3 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 3 seconds    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P02044(ZFAND3 Antibody) at dilution 1/75. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P02044(ZFAND3 Antibody) at dilution 1/75. (Original magnification: ×200)    

  
  

ZFAND3 antibody targets the protein encoded by the ZFAND3 gene, which belongs to the AN1-type zinc finger protein family. This protein contains an N-terminal zinc finger domain and a C-terminal AN1 domain, suggesting roles in protein-protein interactions, ubiquitination pathways, or stress response regulation. ZFAND3 is implicated in cellular processes like protein degradation, transcriptional regulation, and cellular homeostasis, though its precise molecular mechanisms remain understudied.

ZFAND3 antibodies are widely used in research to detect and analyze protein expression, localization, and function via techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Studies associate ZFAND3 with diseases including cancer (e.g., hepatocellular carcinoma), diabetes, and neurological disorders, where its dysregulation may influence disease progression. For example, elevated ZFAND3 levels correlate with tumor growth and poor prognosis in some cancers.

Current research focuses on clarifying ZFAND3’s binding partners, post-translational modifications, and regulatory pathways. Commercially available antibodies are typically raised in rabbits or mice, with validation data confirming specificity for human, mouse, or rat samples. However, some cross-reactivity or variability between antibody clones has been reported, necessitating careful experimental optimization. As interest grows in targeting ubiquitination pathways for therapeutics, ZFAND3 antibodies may gain relevance in diagnostics and drug development. Further functional studies are needed to fully elucidate its biological significance.