STX7抗体

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     Microtiter wells were coated with human immunoglobulins with various isotypes. P15010 was used as the primary antibody and peroxidase conjugated goat anti-mouse IgG was used as the secondary antibody. Result: P15010 does not cross-react with human IgG1, IgG2, IgG4, IgA, IgM and IgE.    

  
  

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     Lane 1: 100 ng of human IgG1;  Lane 2: 100 ng of human IgG2;  Lane 3: 100 ng of human IgG3;Lane 4: 100 ng of human IgG4;  Lane 5: 100 ng of human IgA;  Lane 6: 100 ng of human IgM;  Lane 7: 100 ng of human IgE;  Lane 8: 100 ng of rat IgG1 ;  Result: P15010 can specifically detect human IgG3 by Western blotting;    

  
  

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     IHC-P analysis of human tonsil tissue by anti-human IgG3 antibody (P15010) IHC-P was performed using sections of the formalin-fixed paraffin-embedded human tonsil tissue;Result: Germinal center cells and squamous epithelial cells are positively stained at cytoplasm (Only positively stained germinal center cells are shown here).    

  
  

The STX7 antibody is a tool used to detect Syntaxin 7. a member of the SNARE (Soluble NSF Attachment Protein Receptor) protein family involved in intracellular membrane trafficking and fusion. Syntaxin 7 localizes primarily to late endosomes and lysosomes, where it facilitates vesicle docking and cargo transport, particularly in endocytic and autophagic pathways. Research on STX7 has highlighted its role in organelle maturation, phagosome-lysosome fusion, and autophagy, processes critical for cellular homeostasis and immune responses.

Antibodies targeting STX7 are widely employed in studies investigating membrane dynamics, vesicle trafficking, and lysosomal function. They enable detection of Syntaxin 7 expression levels, subcellular localization, and interactions via techniques like Western blotting, immunofluorescence, and immunoprecipitation. These applications are pivotal in understanding pathologies linked to trafficking defects, such as neurodegenerative diseases, cancer, and immune disorders.

STX7 antibodies are often validated in models ranging from mammalian cell lines to knockout organisms to ensure specificity. Recent studies also explore STX7's involvement in infection mechanisms, as pathogens may exploit host trafficking machinery. Despite its established roles, ongoing research aims to clarify its regulatory mechanisms and tissue-specific functions, underscoring the antibody's continued relevance in cell biology and translational research.