STC1抗体

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     The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P01845(STC1 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P01845(STC1 Antibody) at dilution 1/20. (Original magnification: ×200)    

  
  

**Background of STC1 Antibody**

Stanniocalcin-1 (STC1) is a secreted glycoprotein encoded by the *STC1* gene, initially identified for its role in calcium and phosphate homeostasis in fish. In mammals, STC1 has diverse physiological and pathological functions, including regulating cell metabolism, inflammation, apoptosis, and tumor progression. It is expressed in various tissues, such as the kidneys, intestines, and reproductive organs, and is often upregulated under hypoxic or stressful conditions.

STC1 has gained attention in cancer research due to its overexpression in multiple malignancies, including breast, ovarian, and colorectal cancers. It promotes tumor growth, angiogenesis, and metastasis by modulating signaling pathways like HIF-1α, Wnt/β-catenin, and PI3K/AKT. The STC1 antibody is a critical tool for detecting and quantifying STC1 protein levels in research and diagnostics. It is widely used in techniques like Western blotting, immunohistochemistry (IHC), and ELISA to study STC1’s expression patterns, interactions, and mechanisms in disease models.

Recent studies also explore STC1’s potential as a therapeutic target or biomarker. Antibody-based strategies, such as neutralizing antibodies, are being investigated to block STC1’s oncogenic effects. However, its dual roles in tissue protection and disease pathogenesis necessitate further research to clarify context-specific functions. The STC1 antibody remains vital for advancing our understanding of this multifunctional protein in health and disease.