PTPMT1抗体

+ +

•  

   

     Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal muscle tissue, Primary antibody: P01678(PTPMT1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    

  
  

**Background of PTPMT1 Antibody**

PTPMT1 (Protein Tyrosine Phosphatase Mitochondrial 1) is a dual-specificity phosphatase localized primarily within mitochondria. It belongs to the protein tyrosine phosphatase (PTP) family and is involved in regulating phosphoinositide metabolism by dephosphorylating phosphatidylinositol phosphates (PIPs). PTPMT1 plays a critical role in maintaining mitochondrial function, including energy metabolism, membrane integrity, and apoptosis. Studies suggest its involvement in insulin secretion, cancer progression, and cardiac protection, highlighting its broader physiological and pathological relevance.

Antibodies targeting PTPMT1 are essential tools for studying its expression, localization, and molecular interactions. They are widely used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to investigate PTPMT1's role in cellular processes. Research utilizing these antibodies has revealed PTPMT1's association with metabolic disorders and tumorigenesis, making it a potential therapeutic target. Commercial PTPMT1 antibodies are typically validated for specificity against human, mouse, or rat isoforms, enabling cross-species studies. Ongoing research continues to uncover its regulatory mechanisms, emphasizing the importance of reliable antibody reagents in advancing mitochondrial biology and disease-related discoveries.