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ENTR1抗体

Rabbit Polyclonal ENTR1 Antibody
询价 20μl 起订
50μl 起订
100μl 起订
湖北 更新日期:2025-05-11

湖北瑞和宁生物科技有限公司

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产品详情:

中文名称:
ENTR1抗体
英文名称:
Rabbit Polyclonal ENTR1 Antibody
品牌:
艾普蒂
产地:
武汉
保存条件:
Stored at -20°C for 1661 year. Avoid repeated freeze / thaw cycles.
产品类别:
抗体
重组:
应用:
WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性:
Human,Mouse,Rat
宿主:
Rabbit
偶联物:
靶点:
ENTR1

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesNY-CO-3; SDCCAG3
WB Predicted band size48 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human ENTR1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human prostate tissue, Primary antibody: P00317(ENTR1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P00317(ENTR1 Antibody) at dilution 1/30. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human brain tissue using P00317(ENTR1 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

参考文献

以下是关于ENTR1抗体的模拟参考文献示例(请注意,这些文献为虚构案例,实际检索可能需要调整关键词或验证名称准确性):

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1. **标题**:*Development of a Monoclonal Antibody Specific to ENTR1 for Neural Crest Cell Identification*

**作者**:Miller, K.L., et al.

**摘要**:研究团队开发了一种针对ENTR1蛋白的单克隆抗体,用于识别神经嵴细胞。通过免疫荧光和流式细胞术验证,该抗体在小鼠模型中特异性标记肠道神经嵴前体细胞,为发育生物学研究提供工具。

2. **标题**:*ENTR1 Antibody-Based Detection of Enteric Glial Cells in Inflammatory Bowel Disease*

**作者**:Chen, H., et al.

**摘要**:利用ENTR1多克隆抗体分析炎症性肠病患者肠道组织,发现ENTR1在肠胶质细胞中显著上调,提示其参与肠道炎症反应,可能成为治疗靶点。

3. **标题**:*Validation of ENTR1 Antibody for Immunoblotting and Immunoprecipitation in Cancer Models*

**作者**:Rodriguez, P., et al.

**摘要**:研究验证了ENTR1抗体在免疫印迹和免疫沉淀中的特异性,证实其在结直肠癌细胞系中可靠检测ENTR1蛋白表达,并用于探究其与Wnt信号通路的相互作用。

4. **标题**:*Role of ENTR1 in Neuronal Migration: Insights from Antibody Blockade Experiments*

**作者**:Tanaka, Y., et al.

**摘要**:通过抗ENTR1抗体阻断实验,发现ENTR1在神经元迁移中起关键作用,为神经发育障碍的机制研究提供新方向。

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**建议**:若需真实文献,请核实“ENTR1”名称准确性(如是否指ENT1/SLC29A1或其他蛋白),并检索PubMed/Google Scholar等平台。可尝试关键词组合(如“ENTR1 antibody”、“ENTR1 protein”或潜在别名)。

       

背景信息

The ENTR1 antibody targets the Equilibrative Nucleoside Transporter 1 (ENT1. also known as SLC29A1), a transmembrane protein responsible for the cellular uptake of nucleosides and nucleoside analogs. ENTR1 plays a critical role in regulating extracellular nucleoside concentrations, impacting processes like DNA synthesis, cell signaling, and drug pharmacokinetics. It is widely expressed in tissues, including the liver, kidneys, and brain, and is particularly significant in cancer research due to its involvement in the transport of chemotherapeutic agents such as gemcitabine and 5-fluorouracil. Dysregulation of ENTR1 has been linked to drug resistance in malignancies, making it a focus for therapeutic strategies.

The ENTR1 antibody is utilized in research to study protein expression, localization, and function via techniques like Western blotting, immunohistochemistry, and flow cytometry. It aids in understanding ENTR1’s role in physiological processes (e.g., adenosine signaling in cardiovascular and neurological systems) and pathological conditions, including cancer, viral infections, and inflammatory diseases. Recent studies also explore ENTR1’s interaction with viral proteins, such as hepatitis C virus core proteins, suggesting broader implications in host-pathogen interactions. As a tool, the antibody supports both basic and translational research, offering insights into nucleoside metabolism and therapeutic targeting.

       
ENTR1抗体;ENTR1;ENTR1 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。

成立日期 (2年)
注册资本 50万(元)
员工人数 1-10人
年营业额 ¥ 100万以内
经营模式 贸易,工厂,试剂,定制,服务
主营行业 中间体,化学试剂

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